HLA-G and MIC expression in tumors and their role in anti-tumor immunity
B Seliger, H Abken, S Ferrone - Trends in immunology, 2003 - cell.com
Non-classical MHC class Ib molecules have attracted growing interest in recent years,
especially because they interact with non-T-cell inhibitory or triggering receptors expressed …
especially because they interact with non-T-cell inhibitory or triggering receptors expressed …
Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition
A Ishitani, N Sageshima, N Lee… - The Journal of …, 2003 - journals.aai.org
In this study we focused on the structure and expression of the HLA-E, F, and G class I
complexes in placental tissue. Structural analysis included an examination of the peptides …
complexes in placental tissue. Structural analysis included an examination of the peptides …
[HTML][HTML] HLA-E allelic variants: correlating differential expression, peptide affinities, crystal structures, and thermal stabilities
Previous studies of HLA-E allelic polymorphism have indicated that balancing selection may
be acting to maintain two major alleles in most populations, indicating that a functional …
be acting to maintain two major alleles in most populations, indicating that a functional …
NK-CTLs, a novel HLA-E-restricted T-cell subset
Natural-killer-cytotoxic T lymphocytes (NK-CTLs) are a subset of CD8+ CTLs that express
HLA (human leukocyte antigen) class I-specific inhibitory receptors. They are detectable in …
HLA (human leukocyte antigen) class I-specific inhibitory receptors. They are detectable in …
[HTML][HTML] The KIR gene cluster
M Carrington, P Norman - 2003 - ncbi.nlm.nih.gov
Killer cell immunoglobulin-like receptors (KIRs) are members of a group of regulatory
molecules found on subsets of lymphoid cells. They were first identified by their ability to …
molecules found on subsets of lymphoid cells. They were first identified by their ability to …
Biochemical features of the MHC-related protein 1 consistent with an immunological function
MJ Miley, SM Truscott, YYL Yu, S Gilfillan… - The Journal of …, 2003 - journals.aai.org
Abstract MHC-related protein (MR) 1 is an MHC class I-related molecule encoded on
chromosome 1 that is highly conserved among mammals and is more closely related to …
chromosome 1 that is highly conserved among mammals and is more closely related to …
HLA-F surface expression on B cell and monocyte cell lines is partially independent from tapasin and completely independent from TAP
N Lee, DE Geraghty - The Journal of Immunology, 2003 - journals.aai.org
In this study we examined HLA-F expression in normal cells and cell lines, with a particular
focus on identifying cells that express surface protein. While HLA-F protein was expressed in …
focus on identifying cells that express surface protein. While HLA-F protein was expressed in …
Altered expression of nonclassical HLA class Ib antigens in human renal cell carcinoma and its association with impaired immune response
J Bukur, B Malenica, C Huber, B Seliger - Human immunology, 2003 - Elsevier
An optimal antitumoral immune response requires the activation of both CD8+ and CD4+ T
lymphocytes by the peptide antigen presentation via the human leukocyte antigen (HLA) …
lymphocytes by the peptide antigen presentation via the human leukocyte antigen (HLA) …
Natural killer receptors in patients with lymphoproliferative diseases of granular lymphocytes
R Zambello, G Semenzato - Seminars in hematology, 2003 - Elsevier
The most relevant criterion for recognizing chronic granular lymphocyte (GL) proliferations,
defined as lymphoproliferative disease of GL (LDGL), has been historically based on the …
defined as lymphoproliferative disease of GL (LDGL), has been historically based on the …
DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3
PJ Norman, BS Carey, HAF Stephens, RW Vaughan - Immunogenetics, 2003 - Springer
Leukocyte immunoglobulin-like receptors (LILRs) resemble killer cell immunoglobulin-like
receptors (KIR) in structure and function and the KIR and LILR gene families form the major …
receptors (KIR) in structure and function and the KIR and LILR gene families form the major …