Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins

IS Wood, P Trayhurn - British journal of nutrition, 2003 - cambridge.org
The number of known glucose transporters has expanded considerably over the past 2
years. At least three, and up to six, Na+-dependent glucose transporters (SGLT1–SGLT6; …

A forty-year memoir of research on the regulation of glucose transport into muscle

JO Holloszy - American Journal of Physiology …, 2003 - journals.physiology.org
This historical review describes the research on the regulation of glucose transport in
skeletal muscle conducted in my laboratory and in collaboration with a number of …

GLUT4 Recycles via a trans-Golgi Network (TGN) Subdomain Enriched in Syntaxins 6 and 16 But Not TGN38: Involvement of an Acidic Targeting Motif

AM Shewan, EM Van Dam, S Martin… - Molecular biology of …, 2003 - Am Soc Cell Biol
Insulin stimulates glucose transport in fat and muscle cells by triggering exocytosis of the
glucose transporter GLUT4. To define the intracellular trafficking of GLUT4, we have studied …

Regulation of the human GLUT4 gene promoter: interaction between a transcriptional activator and myocyte enhancer factor 2A

JB Knight, CA Eyster, BA Griesel… - Proceedings of the …, 2003 - National Acad Sciences
The GLUT4 gene is subject to complex tissue-specific and metabolic regulation, with a
profound impact on insulin-mediated glucose disposal. We have shown, by using transgenic …

Characterisation of mammalian GLUT glucose transporters in a heterologous yeast expression system

R Wieczorke, S Dlugai, S Krampe… - Cellular Physiology and …, 2003 - karger.com
We have developed a new heterologous expression system for mammalian glucose
transporters. The system is based on a Saccharomyces cerevisiae strain completely deleted …

Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes

S Rogers, JD Chandler, AL Clarke, S Petrou… - … and biophysical research …, 2003 - Elsevier
We have recently identified and cloned the cDNA of a new member of the glucose
transporter family that has been designated GLUT12. GLUT12 possesses the structural …

What we know about facilitative glucose transporters: Lessons from cultured cells, animal models, and human studies

N Gorovits, MJ Charron - Biochemistry and Molecular Biology …, 2003 - Wiley Online Library
Glucose uptake by all cells in the organism by glucose transport proteins is among the most
essential processes in life. The process of glucose uptake into tissues is performed by …

Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues

IS Wood, L Hunter, P Trayhurn - Biochemical and biophysical research …, 2003 - Elsevier
We have examined whether GLUT-10 and GLUT-12, members of the Class III group of the
recently expanded family of facilitative glucose transporters, are expressed in adipose …

Effects of exercise and glucose administration on content of insulin-sensitive glucose transporter in equine skeletal muscle

VA Lacombe, KW Hinchcliff… - American journal of …, 2003 - Am Vet Med Assoc
Objective—To characterize insulin-sensitive glucose-transporter (GLUT-4) protein in equine
tissues and determine effects of exercise and glucose administration on content of GLUT-4 …

Aberrant insulin-induced GLUT4 translocation predicts glucose intolerance in the offspring of a diabetic mother

M Thamotharan, RA McKnight… - American Journal …, 2003 - journals.physiology.org
We examined the long-term effect of in utero exposure to streptozotocin-induced maternal
diabetes on the progeny that postnatally received either ad libitum access to milk by being …