Autistic disorder (AutD) is a complex genetic disease. Available evidence suggests that
several genes contribute to the underlying genetic risk for the development of AutD …

There is a general consensus that interplay of genetic and environmental factors leads to an
overactive mucosal immune response, which mediates the tissue damage in inflammatory …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder of late life with
complex inheritance. Mutations in three known genes lead to the rare early-onset autosomal …

Osteoporotic fractures are a major cause of morbidity and mortality in ageing populations.
Osteoporosis, defined as low bone mineral density (BMD) and associated fractures, have …

Crohn disease (CD) and ulcerative colitis (UC) are overlapping chronic inflammatory bowel
diseases (IBDs). Suggestive evidence for linkage at chromosome 7q has been reported for …

We report a genomewide linkage study of type 2 diabetes (T2D [MIM 125853]) in the
Icelandic population. A list of type 2 diabetics was cross-matched with a computerized …

Linkage evidence suggests that chromosome 13 (13q32-33) contains susceptibility genes
for both bipolar disorder and schizophrenia. Recently, genes called" G72" and" G30" were …

We conducted genomewide linkage analyses on 1,152 individuals from 250 families
segregating for bipolar disorder and related affective illnesses. These pedigrees were …

Osteoarthritis (OA) is the most common human joint disease, characterized by loss and/or
remodeling of joint synovium, cartilage, and bone. Here, we describe a genomewide linkage …

We report the results of a genomewide scan for age-related macular degeneration (AMD) in
158 multiplex families. AMD classification was based on fundus photography and was …