The renin–angiotensin system (RAS) plays a pivotal role in the regulation of fluid, electrolyte
balance and blood pressure, and is a modulator of cellular growth and proliferation …

Left ventricular hypertrophy (LVH) is an independent cardiovascular risk factor. Angiotensin
AT1 receptor antagonism has been considered as a specific approach to block the renin …

Abstract Angiotensin II (A-II) receptor (AT1 receptor) blockers (ARB) are a class of
antihypertensive agent. It is known that they suppress signal transduction pathways …

Angiotensin-II receptor blockers (ARBs) have been shown to provide stroke, cardiac and
renal protection in high-risk hypertensive patients. Telmisartan is a powerful and selective …

Endurance exercise training appears to beneficially alter the clinical course of chronic heart
failure. The specific mechanisms responsible for exercise‐induced benefits, however, are …

Background and Purpose: In experimental arterial hypertension, left ventricular hypertrophy
(LVH) becomes pathologic with impaired myocardial function if myocardial fibrosis occurs …

The influence of a low-sodium (LS) diet was assessed on the cardiac and renal alterations
and pro-oxidant effect associated with a 10-day infusion of angiotensin II (200 or 400 ng· kg …

Adrenomedullin (AM) is a potent vasodilating and natriuretic peptide that is thought to play
important roles in cardiovascular function. Whether or not AM is involved in the development …

Angiotensin II (Ang II) exerts a potent growth stimulus on the heart and vascular wall.
Activation of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) …

It is proposed that a locally active, intrinsic renin–angiotensin system (RAS) exists in the
bone marrow (BM) and plays a role in regulating haematopoiesis. Angiotensin II type I …