Reverse vaccinology

M Mora, D Veggi, L Santini, M Pizza, R Rappuoli - Drug discovery today, 2003 - Elsevier
Whole-genome sequencing of bacteria and advances in bioinformatics have revolutionized
the vaccinology field, leading to the identification of potential vaccine candidates without the …

Glycoconjugate vaccines to prevent group B streptococcal infections

LC Paoletti, DL Kasper - Expert opinion on biological therapy, 2003 - Taylor & Francis
Group B Streptococcus (GBS) is an opportunistic pathogen of humans. At-risk populations
include neonates born to colonised mothers, peripartum women, diabetics, and the elderly …

Reverse vaccinology and genomics

R Rappuoli, A Covacci - Science, 2003 - science.org
Reverse Vaccinology and Genomics | Science news careers commentary Journals Science
Science brought to you byGoogle Indexer Log in science science advances science immunology …

Genome-Based Bioinformatic Selection of Chromosomal Bacillus anthracis Putative Vaccine Candidates Coupled with Proteomic Identification of Surface-Associated …

N Ariel, A Zvi, KS Makarova, T Chitlaru… - Infection and …, 2003 - Am Soc Microbiol
Bacillus anthracis (Ames strain) chromosome-derived open reading frames (ORFs),
predicted to code for surface exposed or virulence related proteins, were selected as B …

Genomics and its impact on parasitology and the potential for development of new parasite control methods

JT Ellis, DA Morrison, MP Reichel - DNA and cell biology, 2003 - liebertpub.com
Parasitic organisms remain the scourge of the developed and underdeveloped worlds.
Malaria, schistosomiasis, leishmaniasis, and trypanosomiasis, for example, still result in a …

Development of new vaccines against meningococcal disease

M Bröker - Arzneimittelforschung, 2003 - thieme-connect.com
Meningococcal diseases continue to have a major public health impact in many countries.
Five major groups of Neisseria meningitidis (A, B, C, Y and W135) are responsible for most …

Vaccine development for potential bioterrorism agents

RW Titball, ED Williamson - Current Drug Targets-Infectious …, 2003 - ingentaconnect.com
Vaccines are considered to be one of the most effective ways of combating disease caused
by bioterrorism agents. Such vaccines must be able to provide protection against pathogens …

[HTML][HTML] Custom-made vaccines at speed

J Bradbury - Drug Discovery Today, 2003 - ncbi.nlm.nih.gov
Figure 1. Reverse genetics construction of a vaccine for the H5N1 strain of influenza. Each
plasmid contains an RNA polymerase I promoter to drive viral mRNA and protein production …

[PDF][PDF] Genome-Based Bioinformatic Selection of

SC Velan, AM Friedlander, A Shafferman - Citeseer
Bacillus anthracis (Ames strain) chromosome-derived open reading frames (ORFs),
predicted to code for surface exposed or virulence related proteins, were selected as B …

[引用][C] 微生物功能基因组学研究

黄留玉, 王恒樑, 史兆兴, 朱厚础, 苏国富 - 微生物学报, 2003