Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging

G Aël Chetelat, JC Baron - Neuroimage, 2003 - Elsevier
To accurately predict the development of Alzheimer's disease (AD) at its predementia stage
would be a major breakthrough from both therapeutic and research standpoints. In this …

A critical discussion of the role of neuroimaging in mild cognitive impairment

H Wolf, V Jelic, HJ Gertz, A Nordberg… - Acta Neurologica …, 2003 - Wiley Online Library
Objective–In this paper, the current neuroimaging literature is reviewed with regard to
characteristic findings in mild cognitive impairment (MCI). Particular attention is drawn to the …

Dissociating atrophy and hypometabolism impact on episodic memory in mild cognitive impairment

G Chételat, B Desgranges, V de la Sayette, F Viader… - Brain, 2003 - academic.oup.com
The present study aims to unravel, in the same study, both morphological and functional
specific substrates of encoding versus retrieval deficits in patients with amnestic mild …

Regional cerebral blood flow in Parkinson's disease with and without dementia

MJ Firbank, SJ Colloby, DJ Burn, IG McKeith… - Neuroimage, 2003 - Elsevier
Tc99 HMPAO SPECT and T1 weighted 3D MRI scans were acquired in cognitively intact
subjects with Parkinson's disease (PD)(n= 31), and in PD subjects with dementia (PDD)(n …

18F-fluorodeoxyglucose-positron emission tomography: a new explorative perspective

M Schirmer, KT Calamia, M Wenger, A Klauser… - Experimental …, 2003 - Elsevier
18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a new functional
imaging technique available for clinical and experimental use. 18F-FDG-PET studies can be …

Apolipoprotein E genotype and early Alzheimer's disease: a longitudinal SPECT study

S Sakamoto, H Matsuda, T Asada… - Journal of …, 2003 - Wiley Online Library
ABSTRACT Background and Purpose. To determine the association of the apolipoprotein E
(APOE) genotype and longitudinal changes of regional cerebral blood flow (rCBF) in …

D-Serine alleviates retrograde amnesia of a visual discrimination task in rats with a lesion of the perirhinal cortex

JM Andersen, F Fonnum, T Myhrer - Brain research, 2003 - Elsevier
d-Serine has been suggested to be a potent endogenous glycine-site agonist on the N-
methyl-d-aspartate receptor, thereby having a potential role in the process of learning and …

Methodology for the assessment of the relationship between structural and functional imaging findings in neuroimaging

GJ Garrido, SS Furuie… - Medical Imaging 2003 …, 2003 - spiedigitallibrary.org
Using Statistical Parametric Mapping (SPM), we have implemented methods to investigate
the relation between findings from structural MRI and regional cerebral blood flow (rCBF) …

Nuklearmedizin und Demenz—Anwendung bei Morbus Alzheimer

S Asenbaum - Der Radiologe, 2003 - Springer
Nuklearmedizin bietet bei der Erfassung und Beurteilung eines dementiellen Prozesses
eine Vielzahl von Untersuchungsmöglichkeiten. Anhand des Morbus Alzheimer (DAT) …

[引用][C] 10 PERSPEKTIVEN FÜR FRÜHDIAGNOSE, VERLAUFS-UND THERAPIEBEOBACHTUNG

H Hampel, SJ Teipel, F Faltraco, JC Pruessner