[PDF][PDF] Experimental Production of Peptic ulcer

T Brzozowski - Journal of physiology and pharmacology, 2003 - jpp.krakow.pl
The elucidation of the peptic ulcer disease of the stomach and duodenum has accelerated
dramatically in the last 20 years due to the identification of several techniques, which have …

Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors

K Takeuchi, S Kato, M Takeeda, Y Ogawa… - … of Pharmacology and …, 2003 - ASPET
We investigated the role that prostaglandins (PGs) and EP receptors play in facilitating the
gastroprotective action of capsaicin against HCl/ethanol in rats and mice. Male Sprague …

Endogenous prostaglandin I2 regulates the neural emergency system through release of calcitonin gene related peptide

K Arai, T Ohno, T Saeki, S Mizuguchi, K Kamata… - Gut, 2003 - gut.bmj.com
Background: We previously reported that endogenous prostaglandin I2, generated by a mild
irritant, sensitised calcitonin gene related peptide (CGRP) containing sensory nerves and …

Contribution of capsaicin‐sensitive afferent nerves to rapid recovery from ethanol‐induced gastric epithelial damage in rats

M Sobue, T Joh, T Oshima, H Suzuki… - Journal of …, 2003 - Wiley Online Library
Abstract Background and Aim: It is well known that capsaicin‐sensitive nerve signaling acts
as a protective factor against various ulcerogens. However, the contribution of topical …

Preventive effect of zaprinast and 3-isobutyl, 1-methylxanthine (phosphodiesterase inhibitors) on gastric injury induced by nonsteroidal antiinflammatory drugs in rats

JM Herrerías, JM Esteban… - Digestive diseases and …, 2003 - Springer
Cyclic GMP plays an important role in maintaining homeostasis in the gastric mucosa.
NSAIDs damage the mucosa by mechanisms that may be mediated by alterations in the …