CD8 T cell responses to infectious pathogens

P Wong, EG Pamer - Annual review of immunology, 2003 - annualreviews.org
CD8 T cells respond to viral infections but also participate in defense against bacterial and
protozoal infections. In the last few years, as new methods to accurately quantify and …

Antigen presentation in vaccine development

H Takahashi - Comparative immunology, microbiology and infectious …, 2003 - Elsevier
A variety of microorganisms, nutrients or toxins are generally intrude our body through
mucosal tissues or skin, where equipment for both preventing their invasions and catching …

Regulation of CD8+ T cells undergoing primary and secondary responses to infection in the same host

VP Badovinac, KAN Messingham… - The Journal of …, 2003 - journals.aai.org
Abstract Naive Ag-specific CD8+ T cells expand, contract, and become memory cells after
infection and/or vaccination. Memory CD8+ T cells provide faster, more effective secondary …

[PDF][PDF] Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice

VP Badovinac, SE Hamilton, JT Harty - Immunity, 2003 - cell.com
Perforin-mediated cytotoxicity is essential for clearance of primary LCMV infection. BALB/c-
perforin-deficient (PKO) mice survived LCMV infection by deleting NP 118-specific CD8+ T …

Differences in maintenance of CD8+ and CD4+ bacteria‐specific effector‐memory T cell populations

M Schiemann, V Busch, K Linkemann… - European journal of …, 2003 - Wiley Online Library
Our knowledge about the kinetics and dynamics of complex pathogen‐specific CD8+ T cell
responses and the in vivo development of CD8+ memory T cells has increased substantially …

The induction of HIV Gag-specific CD8+ T cells in the spleen and gut-associated lymphoid tissue by parenteral or mucosal immunization with recombinant Listeria …

C Peters, X Peng, D Douven, ZK Pan… - The Journal of …, 2003 - journals.aai.org
The induction of mucosal immunity is crucial in controlling viral replication during HIV
infection. In this study we compare the ability of a recombinant Listeria monocytogenes that …

Identification of HLA-A* 0201-restricted cytotoxic T lymphocyte epitope from TRAG-3 antigen

B Zhu, Z Chen, X Cheng, Z Lin, J Guo, Z Jia, L Zou… - Clinical cancer …, 2003 - AACR
Purpose: Identification of tumor antigen and subsequent identification of T-cell epitope from
these antigens make specific immunotherapy for malignant tumor applicable. Because …

Enhancing the immunogenicity of bioengineered Listeria monocytogenes by passaging through live animal hosts

C Peters, Y Paterson - Vaccine, 2003 - Elsevier
Bioengineered Listeria monocytogenes can be used as a recombinant bacterial vaccine
vector for the induction of strong cell-mediated immunity to passenger antigens. Listeria …

Identification of CD8 T-Lymphocyte Epitopes in OmpB of Rickettsia conorii

Z Li, CM Díaz-Montero, G Valbuena, XJ Yu… - Infection and …, 2003 - Am Soc Microbiol
ABSTRACT The 1.2-kb DNA fragment of the Rickettsia conorii outer membrane protein B
gene (OmpB451-846) was subcloned using site-specific PCR primers and expressed as six …

Method and apparatus for the production of soluble MHC antigens and uses thereof

W Hildebrand, K Prilliman - US Patent App. 10/022,066, 2003 - Google Patents
The field of the invention relates in general to at least one method and apparatus for the
production of soluble MHC antigens and more particularly, but not by way of limitation, to at …