Evolution, biochemistry and genetics of protein kinase C in fungi

HP Schmitz, JJ Heinisch - Current genetics, 2003 - Springer
From yeast to humans, protein kinase C is an enzyme of central importance in signal
transduction processes. In baker's yeast, Saccharomyces cerevisiae, a single gene …

Gef1p, a New Guanine Nucleotide Exchange Factor for Cdc42p, Regulates Polarity in Schizosaccharomyces pombe

PM Coll, Y Trillo, A Ametzazurra… - Molecular biology of the …, 2003 - Am Soc Cell Biol
Schizosaccharomyces pombe cdc42+ regulates cell morphology and polarization of the
actin cytoskeleton. Scd1p/Ral1p is the only described guanine nucleotide exchange factor …

The small GTPase Rho4 is involved in controlling cell morphology and septation in fission yeast

K Nakano, T Mutoh, R Arai, I Mabuchi - Genes to Cells, 2003 - Wiley Online Library
Abstract Background: Rho family small GTPases have been shown to be involved in various
cellular activities, including the organization of actin cytoskeleton in eukaryotic cells. There …

Rga5p is a specific Rho1p GTPase‐activating protein that regulates cell integrity in Schizosaccharomyces pombe

TM Calonge, M Arellano, PM Coll… - Molecular …, 2003 - Wiley Online Library
Schizosaccharomyces pombe Rho1p regulates (1, 3) β‐d‐glucan synthesis and is required
for cell integrity maintenance and actin cytoskeleton organization, but nothing is known …

Novel Rho GTPase Involved in Cytokinesis and Cell Wall Integrity in the Fission Yeast Schizosaccharomyces pombe

B Santos, J Gutiérrez, TM Calonge, P Pérez - Eukaryotic cell, 2003 - Am Soc Microbiol
ABSTRACT The Rho family of GTPases is present in all eukaryotic cells from yeast to
mammals; they are regulators in signaling pathways that control actin organization and …

Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1

NE Torbett, A Casamassima, PJ Parker - Journal of Biological Chemistry, 2003 - ASBMB
Protein kinase N 1 (PKN1), which in part resembles yeast protein kinase C, has been shown
to be under the control of Rho GTPases and 3-phosphoinositide-dependent kinase 1 …

Role of guanine nucleotide exchange factors for Rho family GTPases in the regulation of cell morphology and actin cytoskeleton in fission yeast

N Iwaki, K Karatsu, M Miyamoto - Biochemical and biophysical research …, 2003 - Elsevier
Rho GTPases regulate fundamental processes including cell morphology and migration in
various organisms. Guanine nucleotide exchange factor (GEF) has a crucial role in …

Ksg1, a homologue of the phosphoinositide‐dependent protein kinase 1, controls cell wall integrity in Schizosaccharomyces pombe

R Gräub, N Hilti, C Niederberger… - Journal of Basic …, 2003 - Wiley Online Library
It has previously been shown that the Schizosaccharomyces pombe mutant ksg1‐358 has a
mating and sporulation defect at 30° C and that it is temperature sensitive for growth at 35° …

Mechanismen der Signalübertragung durch PKC und Rho in Hefe und Säugern

JH Tränkle - 2003 - hss-opus.ub.ruhr-uni-bochum.de
Die Proteinkinase Pkc1p der Hefe\(\textit {Saccharomyces cerevisiae}\) konnte\(\textit {in
vitro}\) als Effektor der GTPase Rho1p identifiziert werden. Diese GTPase …