Plasma membrane channels formed by connexins: their regulation and functions

JC Sáez, VM Berthoud, MC Branes… - Physiological …, 2003 - journals.physiology.org
Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …

New roles for astrocytes: gap junction hemichannels have something to communicate

MVL Bennett, JE Contreras, FF Bukauskas… - Trends in …, 2003 - cell.com
Gap junctions are clusters of aqueous channels that connect the cytoplasm of adjoining
cells. Each cell contributes a hemichannel, or connexon, to each cell–cell channel. The cell …

Altered connexin expression and wound healing in the epidermis of connexin-deficient mice

M Kretz, C Euwens, S Hombach… - Journal of cell …, 2003 - journals.biologists.com
To analyze the effect of connexin loss on the repair of wounded tail skin, we have studied
the following transgenic mouse mutants: connexin30–/–, connexin31–/–and connexin43 Cre …

Gap junction hemichannels in astrocytes of the CNS

JC Sáez, JE Contreras, FF Bukauskas… - Acta physiologica …, 2003 - Wiley Online Library
Connexins are protein subunits that oligomerize into hexamers called connexons, gap
junction hemichannels or just hemichannels. Because some gap junction channels are …

[HTML][HTML] Roles of Met-34, Cys-64, and Arg-75 in the assembly of human connexin 26: implication for key amino acid residues for channel formation and function

A Oshima, T Doi, K Mitsuoka, S Maeda… - Journal of Biological …, 2003 - ASBMB
Connexins form a family of membrane proteins that assemble into communication channels
and directly connect the cytoplasms of adjoining cells. Malfunctioning of connexin channels …

Connexin29 and connexin32 at oligodendrocyte and astrocyte gap junctions and in myelin of the mouse central nervous system

JI Nagy, AV Ionescu, BD Lynn… - Journal of Comparative …, 2003 - Wiley Online Library
The cellular localization, relation to other glial connexins (Cx30, Cx32, and Cx43), and
developmental expression of Cx29 were investigated in the mouse central nervous system …

The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer …

T Aasen, MB Hodgins, M Edward, SV Graham - Oncogene, 2003 - nature.com
Disruption of gap junctional intercellular communication (GJIC) and/or connexins (gap
junction proteins) is frequently reported in malignant cell lines and tumours. Certain human …

Gap junctions–from cell to molecule

BJ Nicholson - Journal of cell science, 2003 - journals.biologists.com
Gap junctions were first defined morphologically as specialized contacts between cells that
mediate the direct exchange of small molecules needed to coordinate behavior of …

Cell–cell communication in heterocellular cultures of alveolar epithelial cells

BE Isakson, GJ Seedorf, RL Lubman… - American journal of …, 2003 - atsjournals.org
The mammalian alveolar epithelium is composed of alveolar type I (AT1) and alveolar type II
(AT2) cells that together coordinate tissue function. We used a heterocellular culture model …

A novel function of connexin 32: marked enhancement of liver function in a hepatoma cell line

J Yang, A Ichikawa, T Tsuchiya - Biochemical and Biophysical Research …, 2003 - Elsevier
Connexin 32 (Cx32) is the main gap junction protein in hepatocytes and plays an important
role in the regulation of signal transfer and growth control in the liver by constructing gap …