Autoimmunity and geriatrics: clinical significance of autoimmune manifestations in the elderly
M Ramos-Casals, M Garcia-Carrasco, MP Brito… - Lupus, 2003 - journals.sagepub.com
The immune system undergoes continuousmorphologic and functionalchanges
throughoutthe years, and it is now believed that the immune response has its peak function …
throughoutthe years, and it is now believed that the immune response has its peak function …
Pharmacology and therapeutic effects of dehydroepiandrosterone in older subjects
S Legrain, L Girard - Drugs & aging, 2003 - Springer
Man and higher primates have adrenals that secrete large amounts of
dehydroepiandrosterone (DHEA)[prasterone] and its sulphate (DHEAS)[PB 008]. A …
dehydroepiandrosterone (DHEA)[prasterone] and its sulphate (DHEAS)[PB 008]. A …
Effects of aging on mortality, hypothermia, and cytokine induction in mice with endotoxemia or sepsis
Aging is accompanied by an altered stress response that underlies increased susceptibility
of the elderly patients to physiological stress such as infection and sepsis. In the present …
of the elderly patients to physiological stress such as infection and sepsis. In the present …
Interleukin-6-gene C/G 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for …
IM Rea, OA Ross, M Armstrong, S McNerlan… - Mechanisms of ageing …, 2003 - Elsevier
In this study, we have assessed any change in the frequency of the GG homozygotes of the
174 IL-6 polymorphism with increasing age, arguing that if IL-6 tracks with functional …
174 IL-6 polymorphism with increasing age, arguing that if IL-6 tracks with functional …
Disordered hematopoiesis and myelodysplasia in the elderly
G Rothstein - Journal of the American Geriatrics Society, 2003 - Wiley Online Library
Normal hematopoiesis constitutes the process of producing diverse, differentiated blood cell
types in a manner related to physiological requirement. During aging, modulation of …
types in a manner related to physiological requirement. During aging, modulation of …
Role of redox imbalance in the molecular mechanisms responsible for immunosenescence
RA Daynes, EY Enioutina, DC Jones - Antioxidants and redox …, 2003 - liebertpub.com
The elderly suffer impairments to their immune system, evidenced by higher susceptibility to
infections, cancer, and many diseases believed to be autoimmune in nature. A dysregulated …
infections, cancer, and many diseases believed to be autoimmune in nature. A dysregulated …
Immunology in anxiety and depression
S Andreas, H Florian - Handbook of depression and anxiety, 2003 - taylorfrancis.com
The objectives of psychoneuroimmunology are to elucidate the reciprocal influences of the
nervous system and the immune system and their effects on behavior and health. This field …
nervous system and the immune system and their effects on behavior and health. This field …
Telomerase upregulates expression levels of interleukin (IL)-1α, IL-1β, IL-6, IL-8, and granulocyte–macrophage colony-stimulating factor in normal human fibroblasts
Y Kanzaki, F Onoue, H Sakurai, T Ide - Biochemical and biophysical …, 2003 - Elsevier
Expression of human telomerase reverse transcriptase (hTERT) in normal human fibroblast
cell strain, TIG-3, extends their replicative life span. We found that expression levels of …
cell strain, TIG-3, extends their replicative life span. We found that expression levels of …
Role of the cytokine network in major psychoses
N Müller, MJ Schwarz - Advances in Molecular and Cell Biology, 2003 - Elsevier
Publisher Summary This chapter discusses the recent advances in immunological research
regarding the differentiation between type-1 and type-2 immune response, and specific and …
regarding the differentiation between type-1 and type-2 immune response, and specific and …
The role of nutrition in immunity of the aged
S Walrand, MP Vasson… - Gut Flora, Nutrition …, 2003 - Wiley Online Library
Improvements in health care and nutrition in the last century have increased most people's
life expectancy. One result is that the elderly are now the fastest-growing segment of the …
life expectancy. One result is that the elderly are now the fastest-growing segment of the …