Bacterial meningitis in children

X Sáez-Llorens, GH McCracken - The lancet, 2003 - thelancet.com
This review comprises aspects of the epidemiology, microbiology, pathophysiology, clinical
manifestations, diagnosis, management, prognosis, and prevention of bacterial meningitis …

Reprogramming the host response in bacterial meningitis: how best to improve outcome?

M Van der Flier, SPM Geelen, JLL Kimpen… - Clinical microbiology …, 2003 - Am Soc Microbiol
Despite effective antibiotic therapy, bacterial meningitis is still associated with high morbidity
and mortality in both children and adults. Animal studies have shown that the host …

Secretion of interleukin‐1β by astrocytes mediates endothelin‐1 and tumour necrosis factor‐α effects on human brain microvascular endothelial cell permeability

N Didier, IA Romero, C Créminon… - Journal of …, 2003 - Wiley Online Library
Evidence suggests that endothelin‐1 (ET‐1) plays an essential role in brain inflammation.
However, whether ET‐1 contributes directly to blood–brain barrier (BBB) breakdown …

Lack of IL‐6 augments inflammatory response but decreases vascular permeability in bacterial meningitis

R Paul, U Koedel, F Winkler, BC Kieseier, A Fontana… - Brain, 2003 - academic.oup.com
Abstract Interleukin (IL)‐6 is a multifunctional cytokine with diverse actions and has been
implicated in the pathophysiology of many neurological and inflammatory disorders. In this …

Early neutrophilic expression of vascular endothelial growth factor after traumatic brain injury

A Chodobski, I Chung, E Koźniewska, T Ivanenko… - Neuroscience, 2003 - Elsevier
The formation of edema after traumatic brain injury (TBI) is in part associated with the
disruption of the blood–brain barrier. However, the molecular and cellular mechanisms …

Actions of glucocorticoids and related molecules after traumatic brain injury

JKJ Rhodes - Current Opinion in Critical Care, 2003 - journals.lww.com
Actions of glucocorticoids and related molecules after traum... : Current Opinion in Critical Care
Actions of glucocorticoids and related molecules after traumatic brain injury : Current Opinion …