Pyridoxamine (PM), originally described as a post-Amadori inhibitor of formation of
advanced glycation end-products (AGEs), also inhibits the formation of advanced …

We hypothesized that formation of advanced glycation end products (AGEs) associated with
diabetes reduces matrix degradation by metalloproteinases (MMPs) and contributes to the …

Objective: The inducible isoform of nitric oxide synthase (iNOS) is known to be a trigger of
the heat stress (HS)-induced cardioprotection. Since iNOS also appears to mediate various …

Although the inducible isoform of NO synthase (iNOS) mediates late preconditioning (PC), it
is unknown whether iNOS gene transfer can replicate the cardioprotective effects of late PC …

Although the cardioprotection of late preconditioning (PC) is known to be mediated by both
inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), the signaling mechanism …

The discovery of a novel class of nitric oxide synthase (NOS) inhibitors, 2-substituted 1, 2-
dihydro-4-quinazolinamines, and the related 4 '-aminospiro [piperidine-4, 2 '(1 'H) …

Inducible nitric oxide synthase (iNOS) is a key mediator of inflammation during pathological
conditions. We examined, through the use of selective iNOS inhibitors, the role of iNOS in …

Interleukin-10 (IL-10) is a potent anti-inflammatory cytokine in Th1 cell-mediated chronic
inflammatory diseases such as, eg Crohn's disease. Moreover, IL-10 has been shown to …

Two acidified nitrite-inducible genes of Salmonella enterica serovar Typhimurium were
identified with a green fluorescent protein-based promoter-trap screen. The nitrite-inducible …

Nitric oxide (NO) is implicated in inflammation and hypothalamic–pituitary responses to
immune stimuli; however, the specific role of NO from neurons during stress-induced …