The production of natural antibiotic peptides has emerged as an important mechanism of
innate immunity in plants and animals. Defensins are diverse members of a large family of …

This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …

The surface of the eye is covered by a tear film, which is held in place by a wet-surfaced,
stratified, corneal and conjunctival epithelia. Both are vital for light refraction and protection …

The charge of this invited review is to present a convincing case for the fact that cells release
their ATP for physiological reasons. Many of our “purinergic” colleagues as well as …

Cystic fibrosis (CF) transmembrane conductance regulator (CFTR)-dependent airway
epithelial bicarbonate transport is hypothesized to participate in airway surface liquid pH …

Cystic Fibrosis (CF) lung disease, which is characterized by airway obstruction, chronic
bacterial infection, and an excessive inflammatory response, is responsible for most of the …

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator
(CFTR) protein, an epithelial chloride channel expressed in the airways, pancreas, testis …

In this study, we utilized the reverse transcriptase component of telomerase, hTERT, and
human papillomavirus type 16 (HPV-16) E6 and E7 genes to transform normal and cystic …

Exhaled breath condensates have been widely used to detect inflammatory mediators in the
fluid that covers airway surfaces of patients with inflammatory lung disorders. This approach …

Mucus clearance on airway surfaces is a primary form of pulmonary defense. The efficiency
of mucus clearance in large part depends on the volume of the airway surface liquid …