Novel interactions between K+ channels and scorpion toxins
K+ channels are macromolecules embedded in biological membranes, where they play a
key role in cellular excitability and signal transduction pathways. Knowledge of their …
key role in cellular excitability and signal transduction pathways. Knowledge of their …
Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry
J Liegeois, F Mercier, A Graulich… - Current Medicinal …, 2003 - ingentaconnect.com
Small conductance calcium-activated potassium (SK) channels are found in many types of
neurons as well as in some other cell types. These channels are selective for K+ and open …
neurons as well as in some other cell types. These channels are selective for K+ and open …
Exploration of the functional site of a scorpion α-like toxin by site-directed mutagenesis
CG Wang, N Gilles, A Hamon, F Le Gall… - Biochemistry, 2003 - ACS Publications
Scorpion α-neurotoxins can be classified into distinct subgroups according to their sequence
and pharmacological properties. Using toxicity tests, binding studies, and …
and pharmacological properties. Using toxicity tests, binding studies, and …
Therapy and prophylaxis of inhaled biological toxins
BM Paddle - Journal of Applied Toxicology, 2003 - Wiley Online Library
This review highlights the current lack of therapeutic and prophylactic treatments for use
against inhaled biological toxins, especially those considered as potential biological warfare …
against inhaled biological toxins, especially those considered as potential biological warfare …
[PDF][PDF] Cobatoxin 1 from Centruroides noxius Scorpion Venom: Chemical Synthesis, 3-D Structure in Solution, Pharmacology and Docking on K Channels
B Jouirou, A Mosbah, V Visan, S Grissmer, S M'Barek… - 2003 - researchgate.net
Synopsis Cobatoxin 1 (CoTX1) is a 32 residue toxin with three disulfide bridges that has
been isolated from the venom of the Mexican scorpion Centruroides noxius. Here, we report …
been isolated from the venom of the Mexican scorpion Centruroides noxius. Here, we report …