Animal models of attention-deficit hyperactivity disorder

E Davids, K Zhang, FI Tarazi, RJ Baldessarini - Brain Research Reviews, 2003 - Elsevier
Attention-deficit hyperactivity disorder (ADHD) involves clinically heterogeneous
dysfunctions of sustained attention, with behavioral overactivity and impulsivity, of juvenile …

Genetics of alcohol and tobacco use in humans

RF Tyndale - Annals of medicine, 2003 - Taylor & Francis
The field of genetics holds great promise for furthering our understanding of the etiology of
drug dependence and for identifying novel targets for treatment. Genetic studies utilizing …

Role of dopamine transporter genotype and maternal prenatal smoking in childhood hyperactive-impulsive, inattentive, and oppositional behaviors

RS Kahn, J Khoury, WC Nichols, BP Lanphear - The Journal of pediatrics, 2003 - Elsevier
Objective To examine the joint effects of a dopamine transporter (DAT) polymorphism and
maternal prenatal smoking on childhood hyperactivity-impulsivity and inattentiveness. Study …

Promoter and intronic variants affect the transcriptional regulation of the human dopamine transporter gene

TA Greenwood, JR Kelsoe - Genomics, 2003 - Elsevier
We have attempted to identify regions involved in the transcriptional regulation of the DAT1
(HUGO approved symbol SLC6A3) gene that may harbor functional variants predisposing to …

Dopamine genes and attention-deficit hyperactivity disorder: a review

S DiMaio, N Grizenko, R Joober - Journal of Psychiatry and Neuroscience, 2003 - jpn.ca
Objective: To review the results of genetic studies investigating dopamine-related genes in
attention-deficit hyperactivity disorder (ADHD). Data sources: Papers (association/linkage …

The dopamine transporter and neuroimaging in attention deficit hyperactivity disorder

KH Krause, SH Dresel, J Krause, C la Fougere… - Neuroscience & …, 2003 - Elsevier
There is evidence that abnormalities within the dopamine system in the brain play a major
role in the pathophysiology of attention deficit hyperactivity disorder (ADHD). For instance …

Functional effects of the DAT1 polymorphism on EEG measures in ADHD

SK Loo, E Specter, A Smolen, C Hopfer… - Journal of the American …, 2003 - Elsevier
OBJECTIVE: This paper examines whether dopamine transporter gene (DAT1) allele status
mediates medication-related change in cognitive and neurophysiological measures among …

l -Dopa-induced adverse effects in PD and dopamine transporter gene polymorphism

R Kaiser, A Hofer, A Grapengiesser, T Gasser… - Neurology, 2003 - AAN Enterprises
Objective: To assess whether polymorphisms in the dopamine receptor genes and in the
dopamine transporter gene (DAT) are predictors of adverse effects of l-dopa. Methods: A …

[图书][B] Reducing adolescent risk: Toward an integrated approach

D Romer - 2003 - books.google.com
Reducing Adolescent Risk: Toward an Integrated Approach focuses on common influences
that result in a number of interrelated risk behaviors in order to design more unified …

Effects of dopamine transporter and receptor polymorphisms on smoking cessation in a bupropion clinical trial.

C Lerman, PG Shields, EP Wileyto, J Audrain… - Health …, 2003 - psycnet.apa.org
This study examined the role of dopaminergic genes in prospective smoking cessation and
response to bupropion treatment in a placebo-controlled clinical trial. Smokers of European …