Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure‐induced neurogenesis in the dentate gyrus
The neuropeptide galanin has been implicated in inhibiting seizures and protecting
hippocampal neurons from excitotoxic injury. In the hippocampus galanin acts through two …
hippocampal neurons from excitotoxic injury. In the hippocampus galanin acts through two …
Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice
The neuropeptide galanin is expressed in sympathetic nerve terminals that surround islet
cells and inhibits insulin secretion. To explore its role for islet function, we studied mice with …
cells and inhibits insulin secretion. To explore its role for islet function, we studied mice with …
Neurotrophic influences on neuropathic pain
SB McMahon, WBJ Cafferty - Pathological Pain: From …, 2004 - Wiley Online Library
Damage to peripheral nerves following trauma or disease has a number of consequences
including the emergence of neuropathic pain. Commonly, neuropathic pain sufferers …
including the emergence of neuropathic pain. Commonly, neuropathic pain sufferers …
Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5
XY Hua, CS Hayes, A Hofer, B Fitzsimmons… - … of Pharmacology and …, 2004 - ASPET
The neuropeptide galanin (Gal) and its receptors (GalR1, GalR2, and GalR3) are expressed
in spinal cord. We have characterized the pharmacology of the antinociceptive effects of …
in spinal cord. We have characterized the pharmacology of the antinociceptive effects of …
Pro-nociceptive role of peripheral galanin in inflammatory pain
JM Jimenez-Andrade, S Zhou, J Du, A Yamani… - Pain, 2004 - Elsevier
We investigated the peripheral function of galanin (GAL) in capsaicin (CAP)-induced
inflammatory pain. Intraplantar GAL (0.1 ng/μl) alone does not produce nociceptive …
inflammatory pain. Intraplantar GAL (0.1 ng/μl) alone does not produce nociceptive …
Galanin and cognition
JK Robinson - Behavioral and Cognitive Neuroscience …, 2004 - journals.sagepub.com
Since the neuropeptide galanin's discovery in 1983, information has accumulated that
implicates it in a wide range of functions, including pain sensation, stress responses …
implicates it in a wide range of functions, including pain sensation, stress responses …
Obesity and endocrine dysfunction in mice with deletions of both neuropeptide Y and galanin
JG Hohmann, DN Teklemichael… - … and cellular biology, 2004 - Am Soc Microbiol
Neuropeptide Y (NPY) and galanin have both been implicated in the regulation of body
weight, yet mice bearing deletions of either of these molecules have unremarkable …
weight, yet mice bearing deletions of either of these molecules have unremarkable …
Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injury
K Hygge-Blakeman, P Brumovsky, JX Hao, XJ Xu… - Brain research, 2004 - Elsevier
The neuropeptide galanin may have a role in modulation of nociception, particularly after
peripheral nerve injury. Here we assessed the development of neuropathic pain-like …
peripheral nerve injury. Here we assessed the development of neuropathic pain-like …
An in vivo mouse spinal cord preparation for patch-clamp analysis of nociceptive processing
BA Graham, AM Brichta, RJ Callister - Journal of neuroscience methods, 2004 - Elsevier
The laboratory mouse is now considered the preferred mammalian species for molecular
and genetic analysis in neurobiology. In part, this is due to the existence, in the mouse, of …
and genetic analysis in neurobiology. In part, this is due to the existence, in the mouse, of …
Functional organization of dorsal horn interneurons
WD Willis, RE Coggeshall, WD Willis… - Sensory Mechanisms of …, 2004 - Springer
Sensory processing in the spinal cord involves interactions among primary afferent fibers
bearing information from sensory receptors, interneurons, ascending tract cells conveying …
bearing information from sensory receptors, interneurons, ascending tract cells conveying …