Haloperidol (HAL) is a typical neuroleptic that acts primarily as a D2 dopamine receptor
antagonist. It has been proposed that reactive oxygen species play a causative role in …

Typical and atypical antipsychotic drugs have been shown to have different clinical and
behavioral profiles. Haloperidol (HAL) is a typical neuroleptic that acts primarily as a D2 …

The aim of the study was to investigate the lipid peroxidation levels, nitrite formation,
GABAergic and glutamatergic receptor densities in the hippocampus, frontal cortex and …

Previous experiments have shown that the generation of free hydroxyl radicals in rat brain
homogenates is increased following pentylenetetrazol (PTZ) kindling. The present study was …

Topiramate, a new anticonvulsant, has been reported to possess neuroprotective effects in
both in vivo and in vitro experiments. In the present study, the effect of topiramate (40 and 80 …

The mechanism underlying the vulnerability of the brain to status epilepticus (SE) induced
by pilocarpine remains unknown. Oxidative stress has been implicated in a variety of acute …

The role of oxidative stress in electroconvulsive therapy–related effects is not well studied.
The purpose of this study was to determine oxidative stress parameters in several brain …

Although several advances has occurred over the past 20 years concerning the use of
electroconvulsive therapy (ECT), little progress has been made in the mechanisms …

Brain injury was induced by intraperitoneal administration of kainic acid (KA, 10 mg/kg).
Animals were randomized to receive either IRFI 042 (20 mg/kg ip), a lipid peroxidation …