▪ Abstract This review summarizes the major features of CD1 genes and proteins, the
patterns of intracellular trafficking of CD1 molecules, and how they sample different …

Much of the hepatology literature to date has focused on the adaptive, antigen‐specific
response mediated by classical T‐cell populations in both the protection and pathogenesis …

Assessment of cell-mediated toxicity has traditionally been achieved by measuring the
specific activity of enriched effector cell populations against antigen-loaded target cells …

Invariant (inv) NKT cells are a subset of autoreactive lymphocytes that recognize
endogenous lipid ligands presented by CD1d, and are suspected to regulate the host …

The human MHC class I-like molecule CD1b is distinctive among CD1 alleles in that it is
capable of presenting a set of glycolipid species that show a very broad range of variation in …

Abstract A subset of CD161+ CD56+/− NKT cells can recognize glycolipids presented by
CD1d and positively or negatively regulate inflammatory responses, including those …

Natural killer T (NKT) cells constitute a T cell subpopulation that shares several
characteristics with NK cells. NKT cells are characterized by a narrow T cell antigen receptor …

Human Vα24+ natural killer T (NKT) cells have an invariant T-cell receptor-α chain and are
activated in a CD1d-restricted manner. Vα24+ NKT cells are thought to regulate immune …

T cells expressing NK cell receptors (NKR) display rapid MHC‐unrestricted cytotoxicity and
potent cytokine secretion and are thought to play roles in immunity against tumors. We have …

Natural killer (NK) T cells are innate CD1d-restricted immune cells involved in regulation of
immune tolerance, tumor immunity, and immunity to infectious pathogens. Human α-chain …