Principles, techniques, and limitations of near infrared spectroscopy

M Ferrari, L Mottola, V Quaresima - Canadian journal of …, 2004 - cdnsciencepub.com
In the last decade the study of the human brain and muscle energetics underwent a radical
change, thanks to the progressive introduction of noninvasive techniques, including near …

Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy

DA Boas, AM Dale, MA Franceschini - Neuroimage, 2004 - Elsevier
Near-infrared spectroscopy (NIRS) and diffuse optical imaging (DOI) are finding widespread
application in the study of human brain activation, motivating further application-specific …

Lighting up tumors with receptor-specific optical molecular probes

S Achilefu - Technology in cancer research & treatment, 2004 - journals.sagepub.com
Accurate and rapid detection of tumors is of great importance for interrogating the molecular
basis of cancer pathogenesis, preventing the onset of complications, and implementing a …

Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of …

A Liebert, H Wabnitz, J Steinbrink, H Obrig, M Möller… - Applied …, 2004 - opg.optica.org
We report on multidistance time-resolved diffuse reflectance spectroscopy of the head of a
healthy adult after intravenous administration of a bolus of indocyanine green. Intracerebral …

Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green

C Terborg, S Bramer, S Harscher, M Simon… - Journal of Neurology …, 2004 - jnnp.bmj.com
Objective: To detect perfusion reductions in patients with acute cerebral infarcts using near-
infrared spectroscopy (NIRS) with indocyanine green (ICG) as tracer. Methods: Kinetics of …

Cytochrome-c-oxidase redox changes during visual stimulation measured by near-infrared spectroscopy cannot be explained by a mere cross talk artefact

K Uludağ, J Steinbrink, M Kohl-Bareis, R Wenzel… - Neuroimage, 2004 - Elsevier
The detection of redox changes in cytochrome-c-oxidase ([Cyt-ox]) in response to cerebral
activation by non-invasive NIRS is hampered by methodological spectroscopic issues …

Depth of arterial oscillation resolved with NIRS time and frequency domain

G Themelis, J Selb, S Thaker, JJ Stott… - Biomedical Topical …, 2004 - opg.optica.org
We investigated the depth of systemic oscillations, as the heartbeat, always present in the
optical signal. To this aim we performed measurements in the head of humans and piglets …

Assessment of cerebral perfusion by time-resolved diffuse NIR-reflectance following injection of a dye-bolus

A Liebert, H Wabnitz, M Möller… - Biomedical Topical …, 2004 - opg.optica.org
We monitored the passage of an indocyanine green (ICG) bolus through the brain and
extracerebral tissue in healthy volunteers by means of time-resolved diffuse NIR-reflectance …