Biochemistry and biology of mammalian DNA methyltransferases
DNA methylation is a stable but not irreversible epigenetic signal that silences gene
expression. It has a variety of important functions in mammals, including control of gene …
expression. It has a variety of important functions in mammals, including control of gene …
Epigenetics and human disease
Y Jiang, J Bressler, AL Beaudet - Annu. Rev. Genomics Hum …, 2004 - annualreviews.org
▪ Abstract Epigenetics is comprised of the stable and heritable (or potentially heritable)
changes in gene expression that do not entail a change in DNA sequence. The role of …
changes in gene expression that do not entail a change in DNA sequence. The role of …
Toward a discipline of pharmacoepigenomics
M Szyf - Current Pharmacogenomics, 2004 - ingentaconnect.com
This review argues that the epigenome, which plays a critical role in controlling gene
expression, plays also an important role in drug responsiveness. The epigenome is …
expression, plays also an important role in drug responsiveness. The epigenome is …
A complex interplay of regulatory domains controls cell cycle dependent subnuclear localization of DNMT1 and is required for the maintenance of epigenetic …
HP Easwaran - 2004 - edoc.hu-berlin.de
DNA methylation constitutes an essential epigenetic mark controlling chromatin organization
and gene regulation in higher eucaryotes, which has to be duplicated together with the …
and gene regulation in higher eucaryotes, which has to be duplicated together with the …
[图书][B] Cytokine gene regulation during T helper cell differentiation
DU Lee - 2004 - search.proquest.com
Differentiating cells undergo programmed alterations in their patterns of gene expression,
which are often regulated by structural changes in chromatin. T cell receptor (TCR) and …
which are often regulated by structural changes in chromatin. T cell receptor (TCR) and …
Positionsklonierung des Locus für das Myoklonus-Dystonia-Syndrom (MDS) und Untersuchung des Epsilon-Sarkoglykan-Gens (SGCE) auf genomische Prägung
M Grabowski - 2004 - edoc.ub.uni-muenchen.de
Abstract Das Ziel der Arbeit bestand darin, anhand molekulargenetischer Untersuchungen
das krankheitsverursachende Gen für das Myoklonus-Dystonia-Syndrom (MDS) in den …
das krankheitsverursachende Gen für das Myoklonus-Dystonia-Syndrom (MDS) in den …
[图书][B] Characterization of the mouse gene for p66 alpha, a protein associated with the NuRD/Mi-2 histone deacetylase complex
SW Marino - 2004 - search.proquest.com
For at least forty years gene silencing has been a topic of interest among biologists. It is
involved in genome stability, X chromosome inactivation, imprinting, developmental …
involved in genome stability, X chromosome inactivation, imprinting, developmental …
[引用][C] Positionsklonierung des Locus für das Myoklonus-Dystonia-Syndrom (MDS) und Untersuchung des Epsilon-Sarkoglykan-Gens (SGCE) auf genomische …
M Grabowski - München, Univ., Diss., 2004