The broad availability of genetic information and technologies heralds an era when
practitioners will utilise genomic testing to individualise patients' care. Pharmacogenomics …

With the development and introduction of costly new technologies and restrictive drug
budgets, health economic evaluation has gained increasing importance. Health economic …

As health costs in the US soar past $1.5 trillion, much evidence indicates that the nation
does not get good value for its money. It is widely agreed that we could do better by using …

Purpose Trastuzumab therapy has been shown to benefit metastatic breast cancer patients
whose tumors exhibit HER-2 protein overexpression or gene amplification. Several tests of …

ABSTRACT Objective: The US Public Health Service Panel on Cost‐Effectiveness has
recommended the use of quality‐adjusted life‐years (QALYs) as the best way to estimate …

Purpose To compare the societal costs and the (quality-adjusted) life expectancy of patients
with rectal cancer undergoing total mesorectal excision (TME) with or without short-term …

PURPOSE To examine the historical, legal/organizational, informatics, clinical, economic,
and policy contexts underlying economic consequences of nursing diagnoses on patient …

Economic evaluations are increasingly common in blood safety and transfusion medicine.
We sought to summarize and review economic evaluations of donated blood interventions …

We evaluated quality of life (QL) and quality-adjusted survival in International Breast Cancer
Study Group Trial IX, a randomised trial including 1669 eligible patients receiving tamoxifen …

Purpose: To estimate the benefit and cost of using radiotherapy (RT) in the initial
management of lung cancer in the general population. Methods: We identified indications for …