Lnk inhibits Tpo–mpl signaling and Tpo-mediated megakaryocytopoiesis
W Tong, HF Lodish - The Journal of experimental medicine, 2004 - rupress.org
Thrombopoietin (Tpo) is the primary cytokine regulating megakaryocyte development and
platelet production. Tpo signaling through its receptor, c-mpl, activates multiple pathways …
platelet production. Tpo signaling through its receptor, c-mpl, activates multiple pathways …
Molecular mechanisms of megakaryocyte differentiation
H Schulze, RA Shivdasani - Seminars in thrombosis and …, 2004 - thieme-connect.com
Each bone marrow megakaryocyte (MK) releases thousands of platelets into the circulation,
and the underlying molecular and cellular mechanisms recently have received intense …
and the underlying molecular and cellular mechanisms recently have received intense …
Thrombopoietin signalling in physiology and disease
B Fishley, WS Alexander - Growth Factors, 2004 - Taylor & Francis
Thrombopoietin (TPO) is a key physiological regulator of steady-state megakaryocytopoiesis
, the process of megakaryocyte production and maturation that ultimately results in the …
, the process of megakaryocyte production and maturation that ultimately results in the …
Co-infection of malaria and γ-herpesvirus: exacerbated lung inflammation or cross-protection depends on the stage of viral infection
A Haque, N Rachinel, MR Quddus… - Clinical & …, 2004 - academic.oup.com
In order to study the interaction between a γ-herpesvirus and malaria we established a co-
infection model that involves infection of mice with murine γ-herpesvirus (MHV-68) and …
infection model that involves infection of mice with murine γ-herpesvirus (MHV-68) and …
Culture of megakaryocytic cell lines: uses and limitations
N Komatsu - Platelets and Megakaryocytes: Volume 1: Functional …, 2004 - Springer
Megakaryocytes (MKs), the precursors of platelets, constitute only 0.03–0.06% of all
nucleated cells in the bone marrow and are therefore difficult to isolate in large numbers …
nucleated cells in the bone marrow and are therefore difficult to isolate in large numbers …