Matrix metalloproteinases: contribution to pathogenesis, diagnosis, surveillance and treatment of abdominal aortic aneurysms

NP Kadoglou, CD Liapis - Current medical research and opinion, 2004 - Taylor & Francis
Background: Aortic abdominal aneurysm (AAA) represents a common chronic degenerative
disease of the aortic wall. Chronic inflammation and enzymatic degradation of elastic …

Cardiac rupture complicating myocardial infarction

XHT Wehrens, PA Doevendans - International journal of cardiology, 2004 - Elsevier
Rupture of the ventricular free wall is a leading cause of death in patients with acute
myocardial infarction (MI). There are a number of risk indicators that are associated with …

A single nucleotide polymorphism in the matrix metalloproteinase-2 promoter is associated with colorectal cancer

E Xu, M Lai, B Lv, X Xing, Q Huang, X Xia - Biochemical and biophysical …, 2004 - Elsevier
Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity against matrix
proteins, particularly basement membrane constituents. A single nucleotide polymorphism …

Analysis of MMP-1 and MMP-9 promoter polymorphisms in early osseointegrated implant failure.

MCL Santos, MIG Campos, AP Souza… - … Journal of Oral & …, 2004 - search.ebscohost.com
Purpose: Polymorphisms, such as a guanine inserted at position-1607 in the promoter
region of human matrix metalloprotenase 1 (MMP-1) or a C-1562T substitution in the MMP-9 …

Altered arterial homeostasis and cerebral aneurysms: a review of the literature and justification for a search of molecular biomarkers

A Kassam, M Horowitz, YF Chang, D Peters - Neurosurgery, 2004 - journals.lww.com
Abstract DESPITE THE CATASTROPHIC consequence of ruptured intracranial aneurysms,
very little is understood regarding their pathogenesis, and there are no reliable predictive …

Altered arterial homeostasis and cerebral aneurysms: a molecular epidemiology study

AB Kassam, M Horowitz, YF Chang, D Peters - Neurosurgery, 2004 - journals.lww.com
OBJECTIVE: We hypothesized that patients with intracranial cerebral aneurysms (IAs)
harbor a molecular defect in the process responsible for maintaining arterial integrity …

Identifying the combination of genetic factors that determine susceptibility to cervical cancer

JT Horng, KC Hu, LC Wu, HD Huang… - IEEE Transactions …, 2004 - ieeexplore.ieee.org
Cervical cancer is common among women all over the world. Although infection with high-
risk types of human papillomavirus (HPV) has been identified as the primary cause of …

Longer dinucleotide repeat polymorphism in matrix metalloproteinase-9 (MMP-9) gene promoter which correlates with higher HTLV-I Tax mediated transcriptional …

D Kodama, M Saito, W Matsumoto, AH Sabouri… - Journal of …, 2004 - Elsevier
Matrix metalloproteinase-9 (MMP-9) has been reported to be expressed in various
inflammatory disorders including human T cell lymphotropic virus type I (HTLV-I) associated …

Matrix metalloproteinase-9 coding sequence single-nucleotide polymorphisms in caucasians with intracranial aneurysms

D Krex, K Kotteck, IR König, A Ziegler… - …, 2004 - journals.lww.com
OBJECTIVE: There are several lines of evidence suggesting that matrix metalloproteinases
(MMPs), particularly MMP-9, are involved in the pathogenesis of intracranial aneurysms …

Update on genetic evidence for rupture-prone compared with rupture-resistant intracranial saccular aneurysms

VG Khurana, I Meissner, FB Meyer - Neurosurgical focus, 2004 - thejns.org
Object Anecdotal evidence exists for at least two subpopulations of intracranial saccular
aneurysms; those that form rapidly and rupture when small and those that enlarge slowly …