Resistance to contaminants in North American fish populations

I Wirgin, JR Waldman - Mutation Research/Fundamental and Molecular …, 2004 - Elsevier
Fish from urban and industrialized estuaries are exposed among the highest levels of
contaminants of any vertebrate populations. As a result, they serve as especially relevant …

Toxicity of oil sands to early life stages of fathead minnows (Pimephales promelas)

MV Colavecchia, SM Backus… - … and Chemistry: An …, 2004 - Wiley Online Library
The present study examines the effects of exposure to oil sands on the early life stages
(ELS) off fathead minnows (Pimephales promelas). Sediments within and outside natural oil …

2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin activation of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator pathway causes developmental …

SA Carney, RE Peterson, W Heideman - Molecular pharmacology, 2004 - ASPET
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that dimerizes
with ARNT to mediate responses to compounds such as 2, 3, 7, 8-tetrachlorodibenzo-p …

2,3,7,8-Tetrachlorodibenzo-p-Dioxin Inhibits Regression of the Common Cardinal Vein in Developing Zebrafish

SM Bello, W Heideman, RE Peterson - Toxicological Sciences, 2004 - academic.oup.com
A role for the aryl hydrocarbon receptor (AHR) pathway in vascular maturation has been
implicated by studies in Ahr-null mice. In this study the hypothesis that activation of AHR …

Role of Aryl Hydrocarbon Receptor in Mesencephalic Circulation Failure and Apoptosis in Zebrafish Embryos Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

W Dong, H Teraoka, Y Tsujimoto… - Toxicological …, 2004 - academic.oup.com
Abstract 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent and potent
developmental toxicant in various animals, with developing fish being the most sensitive …

Juvenile sea bass biotransformation, genotoxic and endocrine responses to β-naphthoflavone, 4-nonylphenol and 17β-estradiol individual and combined exposures

M Teles, C Gravato, M Pacheco, MA Santos - Chemosphere, 2004 - Elsevier
Juvenile sea bass, Dicentrarchus labrax L., were exposed during 2, 4, 8, and 24 h to 0.9 μM
β-naphthoflavone (BNF), 131 nM 17β-estradiol (E2), 4.05 μM 4-nonylphenol (NP), as well as …

2, 3, 7, 8-TCDD effects on visual structure and function in swim-up rainbow trout

PSM Carvalho, DE Tillitt - Environmental science & technology, 2004 - ACS Publications
An understanding of mechanisms of contaminant effects across levels of biological
organization is essential in ecotoxicology if we are to generate predictive models for …

Baltic salmon (Salmo salar) yolk-sac fry mortality is associated with disturbances in the function of hypoxia-inducible transcription factor (HIF-1α) and consecutive gene …

KAM Vuori, A Soitamo, PJ Vuorinen, M Nikinmaa - Aquatic toxicology, 2004 - Elsevier
Baltic salmon (Salmo salar) suffer from abnormally high yolk-sac fry mortality designated as
M74-syndrome. In 1990s, 25–80% of salmon females, which ascended rivers to spawn …

Bisphenol A induces yolk-sac oedema and other adverse effects in landlocked salmon (Salmo salar m. sebago) yolk-sac fry

JO Honkanen, IJ Holopainen, JVK Kukkonen - Chemosphere, 2004 - Elsevier
Accumulation and toxicity of waterborne bisphenol A were studied in landlocked salmon
(Salmo salar m. sebago) yolk-sac fry. In a short-term (96 h) exposure to five bisphenol A …

Developmental toxicity of dioxin to mouse embryonic teeth in vitro: arrest of tooth morphogenesis involves stimulation of apoptotic program in the dental epithelium

AM Partanen, A Kiukkonen, C Sahlberg… - Toxicology and applied …, 2004 - Elsevier
Previous studies have shown that 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) can arrest
molar tooth development in rats after in utero and lactational exposure, and that the sensitive …