Aquaporins (AQP) are integral membrane proteins that serve as channels in the transfer of
water, and in some cases, small solutes across the membrane. They are conserved in …

The perception of the lens changed remarkably during the career of David Maurice. The
early view was that it was an inert sack of protein that assisted the cornea in focusing light on …

Because of the lack of protein turnover in fiber cells of the ocular lens, Aquaporin 0 (AQP0),
the most abundant membrane protein in the lens, undergoes extensive post-translational …

purpose. The 129 strain of mouse carries a mutation in the gene for CP49 (phakinin), an
intermediate filament protein thus far demonstrated only in the lens fiber cell. As such, these …

We observed that chick lens-fiber gap-junction-forming proteins, connexin (Cx) 45.6 and
Cx56, were associated with an unknown protein, which was then identified as major intrinsic …

Lens major intrinsic protein (MIP), exclusive to the vertebrate lens, otherwise known as
MIP26 and Aquaporin 0, is abundantly expressed as a lens fiber membrane protein …

purpose. Major intrinsic protein (MIP), also called aquaporin-0, is essential for lens
transparency and is specifically expressed in the lens fiber cell membranes. The goal of the …

METHODS All the experiments were performed in accordance with the ARVO Statement for
the Use of Animals in Ophthalmic and Vision Research. All the solvents and chemical …