Desmin: a major intermediate filament protein essential for the structural integrity and function of muscle
D Paulin, Z Li - Experimental cell research, 2004 - Elsevier
Desmin is a muscle-specific protein and a key subunit of the intermediate filament in cardiac,
skeletal and smooth muscles. Desmin filaments are mainly located at the periphery of Z-disk …
skeletal and smooth muscles. Desmin filaments are mainly located at the periphery of Z-disk …
Intermediate filament proteins and their associated diseases
MB Omary, PA Coulombe… - New England Journal of …, 2004 - Mass Medical Soc
Intermediate filaments provide scaffolding for the cell and protect it against stress. This
comprehensive review points out that there are more than 100 intermediate filament genes …
comprehensive review points out that there are more than 100 intermediate filament genes …
Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds
PA Coulombe, P Wong - Nature cell biology, 2004 - nature.com
Intermediate filaments are cytoskeletal polymers encoded by a large family of differentially
expressed genes that provide crucial structural support in the cytoplasm and nucleus of …
expressed genes that provide crucial structural support in the cytoplasm and nucleus of …
The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation?
H Bär, SV Strelkov, G Sjöberg, U Aebi… - Journal of structural …, 2004 - Elsevier
Desmin, the major intermediate filament (IF) protein of muscle, is evolutionarily highly
conserved from shark to man. Recently, an increasing number of mutations of the desmin …
conserved from shark to man. Recently, an increasing number of mutations of the desmin …
Desmin: molecular interactions and putative functions of the muscle intermediate filament protein
ML Costa, R Escaleira, A Cataldo, F Oliveira… - Brazilian journal of …, 2004 - SciELO Brasil
Desmin is the intermediate filament (IF) protein occurring exclusively in muscle and
endothelial cells. There are other IF proteins in muscle such as nestin, peripherin, and …
endothelial cells. There are other IF proteins in muscle such as nestin, peripherin, and …
Structural and functional roles of desmin in mouse skeletal muscle during passive deformation
SB Shah, J Davis, N Weisleder, I Kostavassili… - Biophysical journal, 2004 - cell.com
Mechanical interactions between desmin and Z-disks, costameres, and nuclei were
measured during passive deformation of single muscle cells. Image processing and …
measured during passive deformation of single muscle cells. Image processing and …
Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy
N Weisleder, GE Taffet… - Proceedings of the …, 2004 - National Acad Sciences
One of the hallmarks of cardiomyopathy and heart failure is pronounced and progressive
cardiomyocyte death. Understanding the mechanisms involved in cardiomyocyte cell death …
cardiomyocyte death. Understanding the mechanisms involved in cardiomyocyte cell death …
Muscle-specific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development
AS McElhinny, CN Perry, CC Witt… - Journal of cell …, 2004 - journals.biologists.com
The efficient functioning of striated muscle is dependent upon the structure of several
cytoskeletal networks including myofibrils, microtubules, and intermediate filaments …
cytoskeletal networks including myofibrils, microtubules, and intermediate filaments …
[PDF][PDF] Balancing contractility and energy production: the role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy
MP Czubryt, EN Olson - Recent Prog Horm Res, 2004 - endocrine.org
Cardiac hypertrophy—that is, enlargement of the heart resulting from increased myocyte
size—is observed with many forms of human heart disease. It may arise secondary to an …
size—is observed with many forms of human heart disease. It may arise secondary to an …
[HTML][HTML] Cytoskeletal modulation of electrical and mechanical activity in cardiac myocytes
SC Calaghan, JY Le Guennec, E White - Progress in biophysics and …, 2004 - Elsevier
The cardiac myocyte has an intracellular scaffold, the cytoskeleton, which has been
implicated in several cardiac pathologies including hypertrophy and failure. In this review we …
implicated in several cardiac pathologies including hypertrophy and failure. In this review we …