Abstract Based on the Medical Research Council study, Brown and Brown hypothesized in
1986 that angiotensin II could protect against strokes by causing vasoconstriction of the …

ContextRecent studies suggest that factors other than the degree of carotid stenosis are
involved in ischemic stroke pathogenesis, especially modifications of plaque composition …

Background—Multiple complex stenoses, plaque fissures, and widespread coronary
inflammation are common in acute coronary syndromes. A systemic cause of atherosclerotic …

Flow cytometric studies suggest that platelets are activated in ischaemic stroke or transient
ischaemic attack (TIA). However, few studies have measured circulating leucocyte–platelet …

Background and Purpose—Echo-lucent carotid plaques can be fragile and vulnerable to
rupture, representing a risk factor for ischemic stroke. Given the studies showing that …

Background: Since the validation of carotid endarterectomy (CEA) as an effective means of
stroke prevention, there has been renewed interest in its best indications and methods, as …

Background and Purpose—Fractalkine (FKN), a chemokine expressed by inflamed
endothelium, induces leukocyte adhesion and migration via the receptor CX3CR1. The …

To characterize tissues in atherosclerotic plaques, we have developed a method, the
phased tracking method, for measuring the strain (change in wall thickness) and elasticity of …

The MR imaging of carotid artery and aortic plaque has undergone significant improvement
in the last decade. Early studies utilizing ex vivo specimens and spin echo or fast spin echo …

In our series of studies on noninvasive assessment of the regional elasticity of the arterial
wall, the displacement gradient (change in thickness) of the arterial wall caused by the …