Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimer's disease

L Mosconi, B Nacmias, S Sorbi… - Journal of Neurology …, 2004 - jnnp.bmj.com
Objectives: Declines in brain glucose metabolism have been described early in Alzheimer's
disease (AD), and there is evidence that a genetic predisposition to AD contributes to …

Effects of partial volume correction on discrimination between very early Alzheimer's dementia and controls using brain perfusion SPECT

H Kanetaka, H Matsuda, T Asada, T Ohnishi… - European journal of …, 2004 - Springer
We assessed the accuracy of brain perfusion single-photon emission computed tomography
(SPECT) in discriminating between patients with probable Alzheimer's disease (AD) at the …

Definition, clinical features and neuroanatomical basis of dementia

TJ Grabowski¹, AR Damasio - The neuropathology of dementia, 2004 - books.google.com
Dementia is a frequent consequence of neurodegenerative diseases involving the cerebral
cortex. Unlike stroke, encephalitis or head injury, which lead to relatively circumscribed and …

Age and ApoE genotype interaction in Alzheimer's disease: an FDG-PET study

L Mosconi, S Sorbi, B Nacmias… - Psychiatry Research …, 2004 - Elsevier
Previous positron emission tomography (PET) studies with fluorodeoxglucose (FDG) as
tracer in healthy elders showed that the epsilon4 allele of the apolipoprotein E (ApoE) gene …

Quantitative EEG and perfusional single photon emission computed tomography correlation during long-term donepezil therapy in Alzheimer's disease

G Rodriguez, P Vitali, M Canfora, P Calvini… - Clinical …, 2004 - Elsevier
Objective: There is an increasing interest in the effects of the acetylcholinesterase inhibitors
(AChEIs) in Alzheimer's disease (AD), as investigated by means of objective …

One-year change in cerebral glucose metabolism in patients with Alzheimer's disease

N Hirono, M Hashimoto, K Ishii… - The Journal of …, 2004 - Am Neuropsych Assoc
By using [18F]-2-fluoro-deoxy-d-glucose and positron emission tomography, the authors
studied changes in regional glucose metabolism after a 1-year interval in patients with mild …

Les substrats cérébraux des troubles de la mémoire épisodique dans la maladie d'Alzheimer

B Desgranges, G Chételat, F Eustache - Revue neurologique, 2004 - Elsevier
Résumé L'identification des substrats neuronaux des troubles de la mémoire épisodique
dans la maladie d'Alzheimer peut bénéficier de la tomographie par émission de positons. En …

Longitudinal cerebral perfusion decrease in mild Alzheimer's disease revealed by SPECT with statistical parametric mapping method

YC Lee, RS Liu, YC Liao, PN Wang, KN Lin… - European …, 2004 - karger.com
Fifteen patients with mild Alzheimer's disease received baseline and follow-up technetium-
99m hexamethylpropylene amine oxime SPECT examinations paired with …

Mild Cognitive Impairment (MCI): Predicting Conversion to Clinically Probable Alzheimer's Disease with Fluoro-Deoxy-Glucose PET

JC Baron, G Chételat, B Desgranges… - The Living Brain and …, 2004 - Springer
Optimal implementation of disease-modifying treatment for sporadic Alzheimer's disease
(AD) will require detection of patients at the pre-dementia stage. Resting-state mapping of …

[PDF][PDF] アルツハイマー病の脳SPECT 診断における部分容積効果補正の役割

金高秀和, 松田博史, 朝田隆, 山下典生, 中野正剛… - 東京医科大学 …, 2004 - core.ac.uk
軽度認知障害段階でのアルツハイマー病患者 61 例と対照健常高齢者 61 例を, single photon
emission computed tomography (SPECT) 画像を用いて両者の識別精度を検討した. SPECT …