CD8+ T cell contraction is controlled by early inflammation
VP Badovinac, BB Porter, JT Harty - Nature immunology, 2004 - nature.com
Pathogen-specific CD8+ T cells expand in number after infection and then their numbers
invariably contract by 90–95%, leaving a stable memory cell pool. The chief features of this …
invariably contract by 90–95%, leaving a stable memory cell pool. The chief features of this …
Anthrolysin O and other gram-positive cytolysins are toll-like receptor 4 agonists
Exposure of bone marrow–derived macrophages (BMDMs) to low concentrations of Bacillus
anthracis lethal toxin (LT), whose catalytic subunit is lethal factor (LF), results in induction of …
anthracis lethal toxin (LT), whose catalytic subunit is lethal factor (LF), results in induction of …
Neutrophil involvement in cross-priming CD8+ T cell responses to bacterial antigens
AR Tvinnereim, SE Hamilton, JT Harty - The Journal of Immunology, 2004 - journals.aai.org
Substantial CD8+ T cell responses are generated after infection of mice with recombinant
Listeria monocytogenes strains expressing a model epitope (lymphocytic choriomeningitis …
Listeria monocytogenes strains expressing a model epitope (lymphocytic choriomeningitis …
Growth, Virulence, and Immunogenicity of Listeria monocytogenes aro Mutants
J Stritzker, J Janda, C Schoen, M Taupp… - Infection and …, 2004 - Am Soc Microbiol
Mutants of Listeria monocytogenes with deletions in genes of the common branch of the
biosynthesis pathway leading to aromatic compounds were constructed as possible …
biosynthesis pathway leading to aromatic compounds were constructed as possible …
A structure-based approach for prediction of MHC-binding peptides
Y Altuvia, H Margalit - Methods, 2004 - Elsevier
Identification of immunodominant peptides is the first step in the rational design of peptide
vaccines aimed at T-cell immunity. The advances in sequencing techniques and the …
vaccines aimed at T-cell immunity. The advances in sequencing techniques and the …
Increased dendritic cell numbers impair protective immunity to intracellular bacteria despite augmenting antigen-specific CD8+ T lymphocyte responses
RC Alaniz, S Sandall, EK Thomas… - The Journal of …, 2004 - journals.aai.org
Dendritic cells (DCs) reside in tissues, where they function as sentinels, providing an
essential link between innate and adaptive immunity. Increasing the numbers of DCs in vivo …
essential link between innate and adaptive immunity. Increasing the numbers of DCs in vivo …
Oral Immunization with Recombinant Listeria monocytogenes Controls Virus Load after Vaginal Challenge with Feline Immunodeficiency Virus
R Stevens, KE Howard, S Nordone… - Journal of …, 2004 - Am Soc Microbiol
Recombinant Listeria monocytogenes has many attractive characteristics as a vaccine
vector against human immunodeficiency virus (HIV). Wild-type and attenuated Listeria …
vector against human immunodeficiency virus (HIV). Wild-type and attenuated Listeria …
Identification of a naturally processed cyclin D1 T‐helper epitope by a novel combination of HLA class II targeting and differential mass spectrometry
T‐helper (Th) cells play an important role in orchestrating the effector function of CTL in anti‐
tumor immunity. However, only a limited number of Th cell epitopes has been characterized …
tumor immunity. However, only a limited number of Th cell epitopes has been characterized …
[HTML][HTML] Improved protection conferred by vaccination with a recombinant vaccinia virus that incorporates a foreign antigen into the extracellular enveloped virion
H Kwak, W Mustafa, K Speirs, AJ Abdool, Y Paterson… - Virology, 2004 - Elsevier
Recombinant poxviruses have shown promise as vaccine vectors. We hypothesized that
improved cellular immune responses could be developed to a foreign antigen by …
improved cellular immune responses could be developed to a foreign antigen by …
Utilizing modular neural networks to predict MHC class II-binding peptides
In order to minimize the number of peptides required to be synthesized and to advance the
understanding for the immune response, some researchers have applied the models based …
understanding for the immune response, some researchers have applied the models based …