Ageing is accompanied by 2–4-fold increases in plasma/serum levels of inflammatory
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …

Innate and adaptive immune functions decline with age, leading to increased susceptibility
to infectious diseases and cancer, and reduced responses to preventive vaccination in the …

Plasma and serum biochemical markers proposed for Alzheimer disease (AD) are based on
pathophysiologic processes such as amyloid plaque formation [amyloid β-protein (Aβ), Aβ …

Epidemiologic analyses of current registries indicate that the majority of patients in the
United States with cancer are 65 years old or older. Basic research in both gerontology and …

The expression of a variety of proteins is elevated with aging through unknown mechanisms.
The free radical theory of aging promulgates that reactive oxygen species (ROS) promote …

Objectives: To evaluate the effect of proinflammatory cytokines, their receptors, and
nutritional indicators (at baseline and after 12 weeks of megestrol acetate (MA) treatment) …

The primary aim of this study was to find whether any association exhists between serum
levels of proinflammatory cytokines, mainly IL-6, and the most important comprehensive …

Résumé Les mécanismes responsables de la sarcopénie (fonte de la masse musculaire
avec l'âge) restent mal connus. Le primum movens semble être une moindre réponse …

Longtemps il a été rapporté que l'ensemble des réponses immunitaires déclinait au cours
du vieillissement [1, 2]. Les travaux récents ont montré que ce dogme n'était pas réel, car …

Cellular senescence and malignant transformation share certain basic pathways. In fact,
molecular biologists examining genes that control cellular proliferation and cell death have …