Head and neck squamous cell carcinoma (HNSCC) is one of the most common types of
human cancer, with an annual incidence of more than 500,000 cases worldwide. In the …

Background To assess the prevalence, severity and morbidity of dysphagia following
concurrent chemoradiation for head and neck cancer. Patients and methods Patients who …

Treatment of squamous cell carcinoma of the head and neck (SCCHN) has evolved greatly
in the last two decades, owing to the integration of chemotherapy, advances in …

Purpose: The purpose of this retrospective analysis was to evaluate the emergence of
second primary malignancies and the contribution of different causes of death to the …

Purpose Chemoradiotherapy, the combination of external radiation therapy and concurrent
chemotherapy, has been the basis for the oncologic management of many patients since its …

In 1986, we initiated a multicenter, randomized trial to compare induction chemotherapy with
cisplatin and 5-fluorouracil followed by locoregional treatment (surgery and radiotherapy or …

Purpose To define further the role of concurrent chemoradiotherapy for patients with
advanced squamous carcinoma of the head and neck. Patients and Methods The Radiation …

The primary objective of the present randomized phase III trial was to compare the 3-yr
survival rate of patients treated with standard fractionated radiotherapy (RT) alone or with …

Improving the outcome for patients with locally advanced head and neck carcinomas (HNC)
by rational modification of radiation fractionation regimens or combinations of radiation with …

Purpose The primary objective of this study was to determine the maximum-tolerated dose of
cisplatin that could be added to full-dose gemcitabine and radiation therapy (RT) in patients …