Diversity of inhibitory neurotransmission through GABAA receptors
In the brain, highly connected and heterogeneous GABAergic cells are crucial in controling
the activity of neuronal networks. They accomplish this task by communicating through …
the activity of neuronal networks. They accomplish this task by communicating through …
Analysis of GABAA Receptor Function and Dissection of the Pharmacology of Benzodiazepines and General Anesthetics Through Mouse Genetics
U Rudolph, H Möhler - Annu. Rev. Pharmacol. Toxicol., 2004 - annualreviews.org
GABAA receptors are molecular substrates for the regulation of vigilance, anxiety, muscle
tension, epileptogenic activity, and memory functions, and the enhancement of GABAA …
tension, epileptogenic activity, and memory functions, and the enhancement of GABAA …
Synaptic signaling between GABAergic interneurons and oligodendrocyte precursor cells in the hippocampus
S Lin, DE Bergles - Nature neuroscience, 2004 - nature.com
Oligodendrocyte precursor cells (OPCs) express receptors for many neurotransmitters, but
the mechanisms responsible for their activation are poorly understood. We have found that …
the mechanisms responsible for their activation are poorly understood. We have found that …
γ-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions
SL Boehm II, I Ponomarev, AW Jennings… - Biochemical …, 2004 - Elsevier
γ-Aminobutyric acid A (GABAA) receptors are believed to mediate a number of alcohol's
behavioral actions. Because the subunit composition of GABAA receptors determines …
behavioral actions. Because the subunit composition of GABAA receptors determines …
Effects of status epilepticus on hippocampal GABAA receptors are age-dependent
G Zhang, YH Raol, FC Hsu, DA Coulter… - Neuroscience, 2004 - Elsevier
Long-term GABAA receptor alterations occur in hippocampal dentate granule neurons of
rats that develop epilepsy after status epilepticus in adulthood. Hippocampal GABAA …
rats that develop epilepsy after status epilepticus in adulthood. Hippocampal GABAA …
Parvalbumin‐containing interneurons in the basolateral amygdala express high levels of the α1 subunit of the GABAA receptor
AJ McDonald, F Mascagni - Journal of Comparative Neurology, 2004 - Wiley Online Library
The basolateral amygdala (ABL) is essential for the amnestic effects of benzodiazepines in
aversive learning tasks. Because the α1 subunit of the γ‐aminobutyric acid (GABA) A …
aversive learning tasks. Because the α1 subunit of the γ‐aminobutyric acid (GABA) A …
Chronic unpredictable stress alters gene expression in rat single dentate granule cells
The rat adrenal hormone corticosterone binds to low and high affinity receptors, discretely
localized in brain, including the dentate gyrus. Differential activation of the two receptor …
localized in brain, including the dentate gyrus. Differential activation of the two receptor …
Genetic manipulations of GABAA receptor in mice make inhibition exciting
S Vicini, P Ortinski - Pharmacology & therapeutics, 2004 - Elsevier
The inhibitory neurotransmitter γ-aminobutyric acid (GABA) plays an important role in brain
development and behavior. GABAA receptor subunits knock-out and knock-in mice have …
development and behavior. GABAA receptor subunits knock-out and knock-in mice have …
Quantitative effects produced by modifications of neuronal activity on the size of GABAA receptor clusters in hippocampal slice cultures
S Marty, R Wehrlé, JM Fritschy… - European Journal of …, 2004 - Wiley Online Library
The number and strength of GABAergic synapses needs to be precisely adjusted for
adequate control of excitatory activity. We investigated to what extent the size of GABAA …
adequate control of excitatory activity. We investigated to what extent the size of GABAA …
The α1 and α6 subunit subtypes of the mammalian GABAA receptor confer distinct channel gating kinetics
JL Fisher - The Journal of physiology, 2004 - Wiley Online Library
The GABAA receptors show a large degree of structural heterogeneity, with seven different
subunit families, and 16 different subtypes in mammalian species. The α family is the largest …
subunit families, and 16 different subtypes in mammalian species. The α family is the largest …