Clinical implications of obesity with specific focus on cardiovascular disease: a statement for professionals from the American Heart Association Council on Nutrition …

S Klein, LE Burke, GA Bray, S Blair, DB Allison… - Circulation, 2004 - Am Heart Assoc
Obesity adversely affects cardiac function, increases the risk factors for coronary heart
disease, and is an independent risk factor for cardiovascular disease. The risk of developing …

Use of intramuscular triacylglycerol as a substrate source during exercise in humans

LJC van Loon - Journal of applied physiology, 2004 - journals.physiology.org
Fat and carbohydrate are the principal substrates that fuel aerobic ATP synthesis in skeletal
muscle. Most endogenous fat is stored as triacylglycerol in subcutaneous and deep visceral …

Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease

S Klein, L Fontana, VL Young… - … England Journal of …, 2004 - Mass Medical Soc
Background Liposuction has been proposed as a potential treatment for the metabolic
complications of obesity. We evaluated the effect of large-volume abdominal liposuction on …

[HTML][HTML] Intramuscular fat and glucose tolerance after spinal cord injury–a cross-sectional study

CP Elder, DF Apple, CS Bickel, RA Meyer, GA Dudley - Spinal cord, 2004 - nature.com
Objective: Determine intramuscular fat (IMF) in affected skeletal muscle after complete spinal
cord injury using a novel analysis method and determine the correlation of IMF to plasma …

N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?

J Delarue, C LeFoll, C Corporeau… - Reproduction nutrition …, 2004 - rnd.edpsciences.org
n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA), mainly eicosapentaenoic acid
(EPA, 20: 5 n-3) and docosahexaenoic acid (DHA, 22: 6 n-3), are present in mammal tissues …

Skeletal muscle lipid accumulation in obesity, insulin resistance, and type 2 diabetes

BH Goodpaster, D Wolf - Pediatric diabetes, 2004 - Wiley Online Library
In addition to obesity, many factors, including the distribution of body fat, contribute to the
development of insulin resistance and type 2 diabetes mellitus (T2DM). Lipid contained …

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes

LJC Van Loon, R Koopman… - American Journal …, 2004 - journals.physiology.org
Recent evidence suggests that intramyocellular lipid (IMCL) accretion is associated with
obesity and the development of insulin resistance and/or type 2 diabetes. However, trained …

Exercise training increases intramyocellular lipid and oxidative capacity in older adults

R Pruchnic, A Katsiaras, J He… - American Journal …, 2004 - journals.physiology.org
Intramyocellular lipid (IMCL) has been associated with insulin resistance. However, an
association between IMCL and insulin resistance might be modulated by oxidative capacity …

[HTML][HTML] Gordura visceral, subcutânea ou intramuscular: onde está o problema?

HHM Hermsdorff, JBR Monteiro - Arquivos Brasileiros de …, 2004 - SciELO Brasil
O tecido adiposo é um órgão dinâmico que secreta vários fatores, denominados adipocinas.
Eles estão relacionados, direta ou indiretamente, em processos que contribuem na …

Effects of weight loss and physical activity on muscle lipid content and droplet size

J He, BH Goodpaster, DE Kelley - Obesity research, 2004 - Wiley Online Library
Objectives: To address the potential effects of weight loss and physical activity (WL+ Ex) on
intramyocellular lipid (IMCL) and lipid droplet size in overweight and obese previously …