Novel insights and therapeutical applications in the field of inhibitors of COX-2
W Kiefer, G Dannhardt - Current medicinal chemistry, 2004 - ingentaconnect.com
The discovery of the two isoenzymes COX-1 and COX-2 and the knowledge of their function,
localisation and regulation has initiated the development of COX-2 selective inhibitors …
localisation and regulation has initiated the development of COX-2 selective inhibitors …
Analysis of the analgesic interactions between ketorolac and tramadol during arthritic nociception in rat
The potential advantage of using combination therapy is that analgesia can be maximized
while minimizing the incidence of adverse effects. In order to assess a possible synergistic …
while minimizing the incidence of adverse effects. In order to assess a possible synergistic …
Preoperative rofecoxib oral suspension as an analgesic adjunct after lower abdominal surgery: the effects on effort-dependent pain and pulmonary function
RS Sinatra, QJ Shen, T Halaszynski… - Anesthesia & …, 2004 - journals.lww.com
IMPLICATIONS: Rofecoxib belongs to class of analgesics known as cyclooxygenase-2
inhibitors that reduce pain and inflammation with less risk of bleeding than standard …
inhibitors that reduce pain and inflammation with less risk of bleeding than standard …
Electroacupuncture combined with indomethacin enhances antihyperalgesia in inflammatory rats
RX Zhang, L Lao, X Wang, K Ren… - … Biochemistry and Behavior, 2004 - Elsevier
Our previous study showed that electroacupuncture (EA), an adjuvant to conventional
medicine, significantly attenuated hyperalgesia and inflammation. The present study is an …
medicine, significantly attenuated hyperalgesia and inflammation. The present study is an …
[图书][B] Involvement of the GluR5 kainate receptor subunit in morphine tolerance, but not nociception, acute morphine analgesia, injury-induced hyperalgesia, or …
JJ Bogulavsky - 2004 - search.proquest.com
Glutamate is the major excitatory neurotransmitter in the nervous system and mediates the
transmission of noxious stimuli from the periphery to the central nervous system. The …
transmission of noxious stimuli from the periphery to the central nervous system. The …