OBJECTIVE To determine whether Raman spectroscopy can be used to differentiate
between normal, inflammatory and malignant bladder pathologies in vitro, and secondly if it …

Background & Aims: Identification of preneoplastic changes in histologically normal
epithelium (the “field effect”) could provide a powerful screening tool for colorectal cancer …

OBJECTIVE: The purpose of this study was to assess the in vivo optical detection of high-
grade cervical intraepithelial neoplasia (2/3+) on the whole cervix with a noncontact …

Methods and apparatuses for detecting a condition of a Sample (including cervical cancers
and pre-cancers) through reflectance and/or fluorescence imaging. A Sample is obtained …

Systems and methods are described for improved diagnostic fluorescence and reflectance.
A method of detecting tissue abnormality in a tissue Sample in Vivo detects a Set of …

An aglorithm based on support vector machines (SVM), the most recent advance in pattern
recognition, is presented for use in classifying light-induced autofluorescence collected from …

(57) ABSTRACT A probe for the characterization of optical properties, includ ing Scattering
and absorption properties of a sample, Such as medical and industrial Samples, includes an …

Abstract Background and Objectives The intrinsic fluorescence of carious human teeth, of
different stages of teeth demineralization, and the correspondence of such fluorescence to …

Optical spectroscopy has shown promise as a diagnostic tool for detecting cervical pre-
cancer because spectral variations in optical measurements are closely correlated with the …

Accelerated proliferation of smooth muscle cells (SMC) is known to play an integral role in
atherosclerotic lesion formation. Thus, there has been significant interest in defining both …