Role of viruses in exacerbations of chronic obstructive pulmonary disease

JA Wedzicha - Proceedings of the American Thoracic Society, 2004 - atsjournals.org
Exacerbations of chronic obstructive pulmonary disease (COPD) are a major cause of
morbidity and mortality and hospital admission. Respiratory viral infections, especially …

Bacteria in exacerbations of chronic obstructive pulmonary disease: phenomenon or epiphenomenon?

S Sethi - Proceedings of the American Thoracic Society, 2004 - atsjournals.org
Our understanding of the pathogenesis and consequences of acute exacerbations of
chronic obstructive pulmonary disease (COPD) has increased considerably in the past …

Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease

TMA Wilkinson, GC Donaldson, JR Hurst… - American journal of …, 2004 - atsjournals.org
Treatment of chronic obstructive pulmonary disease (COPD) exacerbations improves
outcomes; however, responses to treatment are variable, and patients with COPD often …

Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study

M Miravitlles, M Ferrer, A Pont, R Zalacain… - Thorax, 2004 - thorax.bmj.com
Background: A study was undertaken to evaluate exacerbations and their impact on the
health related quality of life (HRQL) of patients with chronic obstructive pulmonary disease …

Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease

IS Patel, I Vlahos, TMA Wilkinson… - American journal of …, 2004 - atsjournals.org
Relationships between high-resolution computed tomography (HRCT) findings in chronic
obstructive pulmonary disease (COPD) and bacterial colonization, airway inflammation, or …

Impact of preventing exacerbations on deterioration of health status in COPD

S Spencer, PMA Calverley, PS Burge… - European respiratory …, 2004 - Eur Respiratory Soc
Exacerbations of chronic obstuctive pulmonary disease (COPD) are associated with worse
health status. The Inhaled Steroids in Obstructive Lung Disease in Europe (ISOLDE) study …

Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease

DD Sin, P Lacy, E York, SFP Man - American journal of respiratory …, 2004 - atsjournals.org
Systemic inflammation is present in chronic obstructive pulmonary disease (COPD), which
has been linked to cardiovascular morbidity and mortality. We determined the effects of oral …

Short-term and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitis

R Wilson, L Allegra, G Huchon, JL Izquierdo, P Jones… - Chest, 2004 - Elsevier
Study objectives To compare the effectiveness of oral moxifloxacin with standard antibiotic
therapy in acute exacerbation of chronic bronchitis (AECB). Design Multicenter …

Impact of sputum bacteria on airway inflammation and health status in clinical stable COPD

D Banerjee, OA Khair… - European Respiratory …, 2004 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is characterised by sputum production,
bacterial colonisation, neutrophilic bronchial airway inflammation and poor health status …

[HTML][HTML] COPD exacerbations: the importance of a standard definition

R Pauwels, P Calverley, AS Buist, S Rennard… - Respiratory …, 2004 - Elsevier
Efforts to assess the efficacy of new therapies in the treatment of acute exacerbations of
chronic obstructive pulmonary disease (COPD) have been hampered by the lack of a widely …