Biosynthesis of nonribosomal peptides

R Finking, MA Marahiel - Annu. Rev. Microbiol., 2004 - annualreviews.org
▪ Abstract Bacteria and fungi use large multifunctional enzymes, the so-called nonribosomal
peptide synthetases (NRPSs), to produce peptides of broad structural and biological activity …

Rapid analysis of large protein–protein complexes using NMR-derived orientational constraints: the 95 kDa complex of LpxA with acyl carrier protein

NU Jain, TJO Wyckoff, CRH Raetz… - Journal of molecular …, 2004 - Elsevier
Characterization of protein–protein interactions that are critical to the specific function of
many biological systems has become a primary goal of structural biology research. Analysis …

Mutational analysis of peptidyl carrier protein and acyl carrier protein synthase unveils residues involved in protein− protein recognition

R Finking, MR Mofid, MA Marahiel - Biochemistry, 2004 - ACS Publications
4 '-Phosphopantetheinyl transferases (PPTases) are essential for the production of fatty
acids by fatty acid synthases (primary metabolism) and natural products by nonribosomal …

Mass Spectrometry Assisted Assignment of NMR Resonances in 15N Labeled Proteins

L Feng, R Orlando, JH Prestegard - Journal of the American …, 2004 - ACS Publications
Application of nuclear magnetic resonance (NMR) methods for the structural
characterization to larger and more complex protein systems can be facilitated through the …