Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines
SM Grundy, JI Cleeman, CNB Merz, HB Brewer Jr… - Circulation, 2004 - Am Heart Assoc
The Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program issued
an evidence-based set of guidelines on cholesterol management in 2001. Since the …
an evidence-based set of guidelines on cholesterol management in 2001. Since the …
Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal
JH O'Keefe, L Cordain, WH Harris, RM Moe… - Journal of the American …, 2004 - jacc.org
The normal low-density lipoprotein (LDL) cholesterol range is 50 to 70 mg/dl for native
hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals …
hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals …
Intensive versus moderate lipid lowering with statins after acute coronary syndromes
CP Cannon, E Braunwald, CH McCabe… - New England journal …, 2004 - Mass Medical Soc
Background Lipid-lowering therapy with statins reduces the risk of cardiovascular events,
but the optimal level of low-density lipoprotein (LDL) cholesterol is unclear. Methods We …
but the optimal level of low-density lipoprotein (LDL) cholesterol is unclear. Methods We …
Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled …
ContextThe effect of antihypertensive drugs on cardiovascular events in patients with
coronary artery disease (CAD) and normal blood pressure remains uncertain. ObjectiveTo …
coronary artery disease (CAD) and normal blood pressure remains uncertain. ObjectiveTo …
Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial
ContextLimited data are available evaluating how the timing and intensity of statin therapy
following an acute coronary syndrome (ACS) event affect clinical outcome. ObjectiveTo …
following an acute coronary syndrome (ACS) event affect clinical outcome. ObjectiveTo …
The metabolic syndrome and inflammation
JP Sutherland, B McKinley, RH Eckel - Metabolic syndrome and …, 2004 - liebertpub.com
The metabolic syndrome (MS) is a clustering of cardiovascular risk factors, with insulin
resistance as a major feature. This syndrome has been variously defined, but generally …
resistance as a major feature. This syndrome has been variously defined, but generally …
Lipid-lowering therapy and in-hospital mortality following major noncardiac surgery
PK Lindenauer, P Pekow, K Wang, B Gutierrez… - Jama, 2004 - jamanetwork.com
ContextCardiovascular complications following major noncardiac surgery are an important
source of perioperative morbidity and mortality. Although lipid-lowering medications are …
source of perioperative morbidity and mortality. Although lipid-lowering medications are …
New aspects in the pathogenesis of diabetic atherothrombosis
PR Moreno, V Fuster - Journal of the American College of Cardiology, 2004 - jacc.org
Diabetes mellitus is increasing worldwide, resulting from the interaction of obesity,
inflammation, and hyperglycemia. Activated immunity and cytokine production lead to insulin …
inflammation, and hyperglycemia. Activated immunity and cytokine production lead to insulin …
Clinical outcomes in managed-care patients with coronary heart disease treated aggressively in lipid-lowering disease management clinics: the alliance study
MJ Koren, DB Hunninghake… - Journal of the American …, 2004 - jacc.org
Objectives: This study sought to determine if an aggressive, focused low-density lipoprotein
cholesterol (LDL-C)-lowering strategy was superior to usual care for coronary heart disease …
cholesterol (LDL-C)-lowering strategy was superior to usual care for coronary heart disease …
Markers of inflammation and rapid coronary artery disease progression in patients with stable angina pectoris
E Zouridakis, P Avanzas, R Arroyo-Espliguero… - Circulation, 2004 - Am Heart Assoc
Background—Both endothelial cell activation and macrophage activation play a significant
role in atherogenesis and atheromatous plaque vulnerability and may determine rapid …
role in atherogenesis and atheromatous plaque vulnerability and may determine rapid …