This manuscript reviews the proceedings of a symposium organized by Drs. Antonio
Noronha and Fulton Crews presented at the 2003 Research Society on Alcoholism meeting …

Lipid rafts are membrane microdomains enriched in saturated phospholipids, sphingolipids,
and cholesterol. They have a varied but distinct protein composition and have been …

Stem cells are clonogenic cells with self-renewal and differentiation properties, which may
represent a major target for genetic damage leading to prostate cancer and benign prostatic …

At the onset of neurogenesis in the mammalian central nervous system, neuroepithelial cells
switch from symmetric, proliferative to asymmetric, neurogenic divisions. In analogy to the …

The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early
endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3 …

AC133 is a member of a novel family of cell surface proteins with 5 transmembrane
domains. The function of AC133 is unknown. Although AC133 mRNA is detected in different …

During ontogenesis and the entire adult life hematopoietic stem and progenitor cells have
the capability to migrate. In comparison to the process of peripheral leukocyte migration in …

Prominin-1/CD133 is a five-membrane-span glycoprotein that is thought to act as an
organizer of plasma-membrane protrusions. Here, we report the molecular and cell …

In mammals, embryonic development is more difficult to analyze than in non-mammalian
species because this development occurs in utero. Interestingly, whole embryo culture …

Endocytosis, a process of plasma membrane invaginations, is a fundamental cellular
mechanism, ensuring a number of key functions such as uptake of nutrients, enhanced …