Mathematical modeling of tumor-induced angiogenesis

NV Mantzaris, S Webb, HG Othmer - Journal of mathematical biology, 2004 - Springer
Cancer is a collection of diseases with the common feature of uncontrolled cellular growth.
Most tissues in the body can give rise to cancer, some even yield several types, and each …

Membrane associated proteases and their inhibitors in tumour angiogenesis

A Noel, C Maillard, N Rocks, M Jost… - Journal of clinical …, 2004 - jcp.bmj.com
Cell surface proteolysis is an important mechanism for generating biologically active
proteins that mediate a range of cellular functions and contribute to biological processes …

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

SA Vokes, TA Yatskievych, RL Heimark, J McMahon… - 2004 - journals.biologists.com
During embryonic development, the first blood vessels are formed through the aggregation
and subsequent assembly of angioblasts (endothelial precursors) into a network of …

Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth

K Bajou, C Maillard, M Jost, RH Lijnen, A Gils… - Oncogene, 2004 - nature.com
Plasminogen activator inhibitor type 1 (PAI-1) plays a key role in tumor progression and is
believed to control proteolytic activity and cell migration during angiogenesis. We report …

[HTML][HTML] Inhibition by the soluble syndecan-1 ectodomains delays wound repair in mice overexpressing syndecan-1

V Elenius, M Götte, O Reizes, K Elenius… - Journal of Biological …, 2004 - ASBMB
Wound repair is a tightly regulated process stimulated by proteases, growth factors, and
chemokines, which are modulated by heparan sulfate. To characterize further the role of the …

A key angiogenic role of monocyte chemoattractant protein-1 in hemangioendothelioma proliferation

GM Gordillo, D Onat, M Stockinger… - … of Physiology-Cell …, 2004 - journals.physiology.org
Angiomatous lesions are common in infants and children. Hemangioendotheliomas (HE)
represent one type of these lesions. Endothelial cell proliferation and the development of …

[图书][B] Phytopharmaceuticals in cancer chemoprevention

D Bagchi, HG Preuss - 2004 - taylorfrancis.com
During the past decade, a significant amount of research has been conducted on
phytopharmaceuticals. Today, a growing body of evidence demonstrates the efficacy of a …

Induction of plasminogen activator inhibitor I gene expression by intracellular calcium via hypoxia-inducible factor-1

Q Liu, U Möller, D Flügel, T Kietzmann - Blood, 2004 - ashpublications.org
The plasminogen activator inhibitor-1 (PAI-1) expression can be enhanced by hypoxia and
other stimuli leading to the mobilization of intracellular calcium. Thus, it was the aim of the …

Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids

PE Thorpe, S Ran, RA Brekken - US Patent 6,818,213, 2004 - Google Patents
1999-09-24 Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
reassignment BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM ASSIGNMENT …

Combined cancer treatment methods using therapeutic conjugates that bind to aminophospholipids

PE Thorpe, S Ran, RA Brekken - US Patent 6,783,760, 2004 - Google Patents
2002-02-12 Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
reassignment BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM ASSIGNMENT …