Comparative genomics shows that a substantial fraction of the genes in sequenced
genomes encodes 'conserved hypothetical'proteins, ie those that are found in organisms …

The α-glucosidase inhibitor acarbose, O-{4, 6-dideoxy-4 [1 s-(1, 4, 6/5)-4, 5, 6-trihydroxy-3-
hydroxymethyl-2-cyclohexen-1-yl]-amino-α-d-glucopyranosyl}-(1→ 4)-O-α-d-glucopyranosyl …

Mobilization of fatty acids from triglyceride stores in adipose tissue requires lipolytic
enzymes. Dysfunctional lipolysis affects energy homeostasis and may contribute to the …

Background Sequencing the genomes of multiple, taxonomically diverse eukaryotes
enables in-depth comparative-genomic analysis which is expected to help in reconstructing …

Background The timescale of prokaryote evolution has been difficult to reconstruct because
of a limited fossil record and complexities associated with molecular clocks and deep …

Pole development is coordinated with the Caulobacter crescentus cell cycle by two-
component signaling proteins. We show that an unusual response regulator, PleD, is …

The expression of certain genes involved in fundamental metabolism is regulated by
metabolite-binding “riboswitch” elements embedded within their corresponding mRNAs. We …

The NB mitochondrial genome found in most fertile varieties of commercial maize (Zea mays
subsp. mays) was sequenced. The 569,630-bp genome maps as a circle containing 58 …

Genomic sequences and expressed sequence tag data for a diverse group of fungi
(Saccharomyces cerevisiae, Schizosaccharomyces pombe, Aspergillus nidulans …

Background New techniques for determining relationships between biomolecules of all
types–genes, proteins, noncoding DNA, metabolites and small molecules–are now making …