Ligands for the nuclear receptor superfamily control many aspects of biology, including
development, reproduction, and homeostasis, through regulation of the transcriptional …

Epidemiological studies indicate that normal male aging is associated with a gradual and
variable decline in blood testosterone concentrations and unfavorable changes in muscle …

Increased amount of abdominal fat and obesity are common in polycystic ovary syndrome
(PCOS). A higher prevalence of bulimia nervosa and greater cravings for sweets have also …

Tissue-selective androgen receptor modulators (SARMs) demonstrate tissue selectivity in
both castrated and intact male rats, behaving as partial agonists in androgenic tissues (ie …

Tributyltin (TBT) and triphenyltin (TPT) induce effects in male and female reproductive
organs of rodents. They also cause tumors in these organs and it is theorized that they result …

Androgen-regulated genes (ARGs) are essential for the development of the prostate.
Ironically, ARGs are also responsible for the pathogenesis of prostate cancer. We used …

The transcriptional activity of androgen receptor (AR) is modulated by coregulators that have
a significant influence on a number of functional properties of AR, including the ligand …

Avian egg yolk contains androgenic hormones, such as testosterone, of maternal origin.
Experimental elevation of yolk testosterone levels enhances growth of canary chicks …

BACKGROUND: We investigated the androgen receptor gene GGN polymorphism and its
relation to male infertility and receptor function. METHODS: Ninety-nine infertile patients with …

Acquired anorchia Maldescended testes Klinefelter syndrome XYY syndrome XX male
Noonan syndrome Gonadal dysgenesis Leydig cell tumors Maldescended testes Varicocele …