Aquaporins: water channel proteins of the cell membrane
K Takata, T Matsuzaki, Y Tajika - Progress in histochemistry and …, 2004 - Elsevier
Aquaporins (AQP) are integral membrane proteins that serve as channels in the transfer of
water, and in some cases, small solutes across the membrane. They are conserved in …
water, and in some cases, small solutes across the membrane. They are conserved in …
[HTML][HTML] Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells
V Henn, B Edemir, E Stefan, B Wiesner… - Journal of Biological …, 2004 - ASBMB
Arginine vasopressin (AVP) increases the water permeability of renal collecting duct
principal cells by inducing the fusion of vesicles containing the water channel aquaporin-2 …
principal cells by inducing the fusion of vesicles containing the water channel aquaporin-2 …
cAMP protects endothelial barrier functions by preventing Rac-1 inhibition
J Waschke, D Drenckhahn… - American Journal …, 2004 - journals.physiology.org
cAMP enhances endothelial barrier properties and is protective against various
inflammatory mediators both in vivo and in vitro. However, the mechanisms whereby cAMP …
inflammatory mediators both in vivo and in vitro. However, the mechanisms whereby cAMP …
[HTML][HTML] Non-muscle myosin II and myosin light chain kinase are downstream targets for vasopressin signaling in the renal collecting duct
CL Chou, BM Christensen, S Frische, H Vorum… - Journal of Biological …, 2004 - ASBMB
We have previously demonstrated that vasopressin increases the water permeability of the
inner medullary collecting duct (IMCD) by inducing trafficking of aquaporin-2 to the apical …
inner medullary collecting duct (IMCD) by inducing trafficking of aquaporin-2 to the apical …
Protein kinase A attenuates endothelial cell barrier dysfunction induced by microtubule disassembly
AA Birukova, F Liu, JGN Garcia… - American Journal of …, 2004 - journals.physiology.org
Cross talk between the actin cytoskeleton and the microtubule (MT) network plays a critical
role in regulation of endothelial permeability. We have previously demonstrated that MT …
role in regulation of endothelial permeability. We have previously demonstrated that MT …
Molecular mechanisms and drug development in aquaporin water channel diseases: molecular mechanism of water channel aquaporin-2 trafficking
Y Noda, S Sasaki - Journal of pharmacological sciences, 2004 - Elsevier
Targeted positioning of water channel aquaporin-2 (AQP2) strictly regulates body water
homeostasis. Trafficking of AQP2 to the apical membrane is critical for the reabsorption of …
homeostasis. Trafficking of AQP2 to the apical membrane is critical for the reabsorption of …
Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins
KG Birukov, N Leitinger, VN Bochkov, JGN Garcia - Microvascular research, 2004 - Elsevier
The bioactive component of mildly oxidized low-density lipoproteins, oxidized 1-palmitoyl-2-
arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC), activates tissue factor expression …
arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC), activates tissue factor expression …
PDE4-regulated cAMP degradation controls the assembly of integrin-dependent actin adhesion structures and REF52 cell migration
YM Fleming, MC Frame… - Journal of Cell …, 2004 - journals.biologists.com
Plating of REF52 cells onto extracellular matrix components leads to the formation of integrin-
dependent actin adhesion microspikes. We show that the formation of these structures is …
dependent actin adhesion microspikes. We show that the formation of these structures is …
Aquaporin-2 trafficking
Regulation of the water permeability of the apical plasma membrane in collecting duct
principal cells is essential for the regulation of renal water excretion, and thus, the regulation …
principal cells is essential for the regulation of renal water excretion, and thus, the regulation …