Preconditioning describes the phenomenon by which a traumatic or stressful stimulus
confers protection against subsequent injury. Originally recognized in dog heart subjected to …

Angiogenesis represents a major focus for novel therapeutic approaches to the prevention
and treatment of multiple diseases, most notably ischemic cardiovascular disease and …

Adaptation to intermittent high altitude (IHA) hypoxia can protect the heart against ischemia-
reperfusion injury. In view of the fact that both Ca2+ paradox and ischemia-reperfusion injury …

Intracellular calcium signaling cascade induced by adenosine A3 receptor activation was
studied in this work. It was found that adenosine A3 receptor activation (and not A1 or A2A …

Despite significant advances in myocardial revascularization and reperfusion, coronary
artery disease and subsequently myocardial infarction, are the leading causes of morbidity …

Summary In the Western World ischemic coronary disease is the leading cause of morbidity
and mortality. Therapeutic approaches mostly aim to restore flow to a localized segment by …