Neurone‐to‐astrocyte signalling in the brain represents a distinct multifunctional unit

T Fellin, G Carmignoto - The Journal of physiology, 2004 - Wiley Online Library
Astrocytes can respond to neurotransmitters released at the synapse by generating
elevations in intracellular Ca2+ concentration ([Ca2+] i) and releasing glutamate that signals …

[HTML][HTML] Gap junctions and connexin-mediated communication in the immune system

E Oviedo-Orta, WH Evans - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
Gap junctions and connexins are present in the immune system. In haematopoiesis,
connexin 43, the most widely distributed gap junction protein, appears to be a key player in …

Incorporation of connexins into plasma membranes and gap junctions

PEM Martin, WH Evans - Cardiovascular research, 2004 - academic.oup.com
Gap junctions are polymeric assemblies of aligned pairs of interacting hexameric connexon
hemichannel units facilitating direct intercellular communication. The principal process …

Pharmacology of gap junctions in the cardiovascular system

S Dhein - Cardiovascular research, 2004 - academic.oup.com
Gap junction channels provide the basis for intercellular communication and play an
important physiological role in the cardiovascular system for maintenance of the normal …

Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels

MS Turner, GA Haywood, P Andreka, L You… - Circulation …, 2004 - Am Heart Assoc
Altered gap junction coupling of cardiac myocytes during ischemia may contribute to
development of lethal arrhythmias. The phosphoprotein connexin 43 (Cx43) is the major …

Gap junctional communication and connexin43 expression in relation to apoptotic cell death and survival of granulosa cells

DV Krysko, S Mussche, L Leybaert… - … of Histochemistry & …, 2004 - journals.sagepub.com
Ovarian follicular atresia in all vertebrates is mediated via apoptosis that is initiated in the
granulosa cell layer. Here we investigated the relation between connexin expression, cell …

Gap junction channels coordinate the propagation of intercellular Ca2+ signals generated by P2Y receptor activation

SO Suadicani, CE Flores, M Urban‐Maldonado… - Glia, 2004 - Wiley Online Library
Astrocytes express gap junction proteins and multiple types of P2Y receptors (P2YRs) that
contribute to the propagation of intercellular Ca2+ waves (ICW). To gain access to the role …

Calcium signal communication in the central nervous system

K Braet, L Cabooter, K Paemeleire, L Leybaert - Biology of the Cell, 2004 - Elsevier
The communication of calcium signals between cells is known to be operative between
neurons where these signals integrate intimately with electrical and chemical signal …

Tumour necrosis factor alpha inhibits purinergic calcium signalling in blood–brain barrier endothelial cells

W Vandamme, K Braet, L Cabooter… - Journal of …, 2004 - Wiley Online Library
The breaching of the blood–brain barrier is an essential aspect in the pathogenesis of
neuroinflammatory diseases, in which tumour necrosis factor alpha (TNF‐α) as well as …

The vascular endothelial growth factor‐induced disruption of gap junctions is relayed by an autocrine communication via ATP release in coronary capillary …

D Thuringer - Annals of the New York Academy of Sciences, 2004 - Wiley Online Library
Little is known concerning how the coordination of Ca2+ signaling aids in capillary
endothelial cell (CEC) functions, such as microvascular permeability and angiogenesis …