Role of antioxidants in treatment of male infertility: an overview of the literature

A Agarwal, KP Nallella, SSR Allamaneni… - Reproductive biomedicine …, 2004 - Elsevier
Seminal oxidative stress in the male reproductive tract is known to result in peroxidative
damage of the sperm plasma membrane and loss of its DNA integrity. Normally, a balance …

Andrology lab corner*: role of oxidative stress and antioxidants in andrology and assisted reproductive technology

SC Sikka - Journal of andrology, 2004 - Wiley Online Library
Twenty-five years ago the first human, Louise Brown, was conceived outside the body, and
this event created a new milestone in the history of mankind and the concept of human in …

Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility

MH Moustafa, RK Sharma, J Thornton… - Human …, 2004 - academic.oup.com
BACKGROUND: The aim of this study was to examine the role of apoptosis and reactive
oxygen species (ROS) in inducing DNA damage in ejaculated spermatozoa. METHODS: We …

[HTML][HTML] Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size

SSR Allamaneni, CK Naughton, RK Sharma… - Fertility and sterility, 2004 - Elsevier
Increased levels of reactive oxygen species (ROS) are associated with clinical varicoceles;
however, its correlation with varicocele grade and testis size is unknown. In our study …

Update on the impact of Chlamydia trachomatis infection on male fertility

GF Gonzales, G Munoz, R Sanchez, R Henkel… - Andrologia, 2004 - Wiley Online Library
With approximately 90 million cases annually, infection with Chlamydia trachomatis is the
most prevalent sexually transmitted bacterial disease in the world. Considering that these …

Oxidants and antioxidants in human fertility

A Agarwal, SSR Allamaneni - Middle East Fertility Society Journal, 2004 - bioline.org.br
Oxidants are highly unstable molecules that attack every chemical substance they come into
contact. Oxidants modify the macromolecules both structurally and functionally. Body has …

Relationship of interleukin-6 with semen characteristics and oxidative stress in patients with varicocele

KP Nallella, SSR Allamaneni, FF Pasqualotto… - Urology, 2004 - Elsevier
OBJECTIVES: To examine levels of interleukin-6 (IL-6) in fertile semen donors and patients
with varicocele and examine its association with semen characteristics and levels of reactive …

[HTML][HTML] Human sperm superoxide anion generation and correlation with semen quality in patients with male infertility

TM Said, A Agarwal, RK Sharma, E Mascha, SC Sikka… - Fertility and …, 2004 - Elsevier
OBJECTIVE: To measure levels of reactive oxygen species (ROS) including H2O2 and O2.−
generation in infertile men and determine whether sperm quality is correlated with levels of …

Functional significance of the pentose phosphate pathway and glutathione reductase in the antioxidant defenses of human sperm

AC Williams, WCL Ford - Biology of reproduction, 2004 - academic.oup.com
Glutathione peroxidase is one of the principal antioxidant defense enzymes in human
spermatozoa, but it requires oxidized glutathione to be reduced by glutathione reductase …

[HTML][HTML] Yq microdeletions—azoospermia factor candidate genes and spermatogenic arrest

R Dada, NP Gupta, K Kucheria - Journal of biomolecular …, 2004 - ncbi.nlm.nih.gov
In the last few years considerable progress has been made in the study of sperm physiology
and the biology of gamete interaction, furthering our understanding of the pathophysiology …