Apoptosis regulation in the mammary gland
KA Green, CH Streuli - Cellular and Molecular Life Sciences, 2004 - Springer
Epithelial apoptosis has a key role in the development and function of the mammary gland. It
is involved with the formation of ducts during puberty and is required to remove excess …
is involved with the formation of ducts during puberty and is required to remove excess …
Testosterone-dependent variations in plasma and intrapituitary corticosteroid binding globulin and stress hypothalamic-pituitary-adrenal activity in the male rat
Inhibins are gonadal glycoprotein hormones whose main endocrine function is to inhibit
pituitary FSH secretion. In addition to testes and ovaries, other steroid-producing organs are …
pituitary FSH secretion. In addition to testes and ovaries, other steroid-producing organs are …
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3
T Stein, JS Morris, CR Davies, SJ Weber-Hall… - Breast Cancer …, 2004 - Springer
Introduction Involution of the mammary gland is a complex process of controlled apoptosis
and tissue remodelling. The aim of the project was to identify genes that are specifically …
and tissue remodelling. The aim of the project was to identify genes that are specifically …
Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression
RWE Clarkson, MT Wayland, J Lee, T Freeman… - Breast Cancer …, 2004 - Springer
Introduction In order to gain a better understanding of the molecular processes that underlie
apoptosis and tissue regression in mammary gland, we undertook a large-scale analysis of …
apoptosis and tissue regression in mammary gland, we undertook a large-scale analysis of …
Serotonin regulates mammary gland development via an autocrine-paracrine loop
M Matsuda, T Imaoka, AJ Vomachka, GA Gudelsky… - Developmental cell, 2004 - cell.com
Mammary gland development is controlled by a dynamic interplay between endocrine
hormones and locally produced factors. Biogenic monoamines (serotonin, dopamine …
hormones and locally produced factors. Biogenic monoamines (serotonin, dopamine …
Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice
KU Wagner, A Krempler, AA Triplett, Y Qi… - … and cellular biology, 2004 - Taylor & Francis
Jak2 is a hormone-receptor-coupled kinase that mediates the tyrosine phosphorylation and
activation of signal transducers and activators of transcription (Stat). The biological …
activation of signal transducers and activators of transcription (Stat). The biological …
Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers
I Cotarla, S Ren, Y Zhang, E Gehan… - … journal of cancer, 2004 - Wiley Online Library
Signal transducers and activators of transcription (STATs) are latent cytoplasmic
transcription factors that are activated and translocated into the nucleus after …
transcription factors that are activated and translocated into the nucleus after …
Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium
H Kiaris, K Politi, LM Grimm, M Szabolcs… - The American journal of …, 2004 - Elsevier
Deregulation of Notch signaling, which normally affects a broad spectrum of cell fates, has
been implicated in various neoplastic conditions. Here we describe a transgenic mouse …
been implicated in various neoplastic conditions. Here we describe a transgenic mouse …
Deregulation of Stat5 expression and activation causes mammary tumors in transgenic mice
E Iavnilovitch, RD Cardiff, B Groner… - International journal of …, 2004 - Wiley Online Library
Members of the signal transducers and activators of transcription (Stat) family regulate
essential cellular growth and survival functions in normal cells and have also been …
essential cellular growth and survival functions in normal cells and have also been …
Growth hormone increases Stat5 and Stat1 expression in lactating goat mammary gland: a specific effect compared to milking frequency
M Boutinaud, H Jammes - Domestic Animal Endocrinology, 2004 - Elsevier
In ruminants, both milking frequency and exogenous GH treatment affect milk production. In
a previous report, we showed that the modulation of milk yield due to variations in milking …
a previous report, we showed that the modulation of milk yield due to variations in milking …