The transient receptor potential (TRP) superfamily comprises a group of non-selective cation
channels that sense and respond to changes in their local environments. TRP channels are …

Life expectancy for patients suffering from prostate cancer is inversely correlated with the
degree of extraprostatic metastasis. In order to find pharmacological tools to treat this …

One of the major problems in management of prostate cancer is the lack of reliable genetic
markers predicting the clinical course of the disease. We analyzed expression profiles of …

The Ca2+-permeable channel TRPM8 is thought to play an important role in the
pathophysiology of prostate cancer. We have investigated the intracellular location of …

Purpose: A better understanding of the molecular pathways underlying the development of
epithelial ovarian cancer (EOC) is critical to identify ovarian tumor markers for use in …

Objective Osteoarthritis (OA), characterized by late‐onset degeneration of articular cartilage,
is recognized to have a genetic component. We examined the role of 26 single‐nucleotide …

Prostate cancer is the most commonly diagnosed non-cutaneous neoplasm among
American males and is the second leading cause of cancer-related death. Prostate specific …

BACKGROUND The role of the bone morphogenetic protein (BMP) pathway in prostate
cancer (PC) is unclear. This study aimed to characterize aspects of the BMP pathway in PC …

Current treatments for advanced stage, hormone-resistant prostate cancer are largely
ineffective, leading to high patient mortality and morbidity. To fulfill this unmet medical need …

PURPOSE: Prostate cancer represents a disease with diverse clinical outcomes. Treatment
strategies that optimize benefit and minimize morbidities depend on accurate estimates of …