Modulation of phagocyte apoptosis by bacterial pathogens

FR DeLeo - Apoptosis, 2004 - Springer
Phagocytic leukocytes such as neutrophils and macrophages are essential for the innate
immune response against invading bacteria. Binding and ingestion of bacteria by these host …

Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer

V Punj, S Bhattacharyya, D Saint-Dic, C Vasu… - Oncogene, 2004 - nature.com
Azurin, a copper-containing redox protein released by the pathogenic bacterium
Pseudomonas aeruginosa, is highly cytotoxic to the human breast cancer cell line MCF-7 …

Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin

T Yamada, Y Hiraoka, M Ikehata… - Proceedings of the …, 2004 - National Acad Sciences
The tumor suppressor protein p53 is known to induce either apoptosis or growth arrest
depending on cellular background. We have previously reported that a bacterial redox …

Regulation of mammalian cell growth and death by bacterial redox proteins: relevance to ecology and cancer therapy

T Yamada, Y Hiraoka, TKD Gupta, AM Chakrabarty - Cell Cycle, 2004 - Taylor & Francis
Recent evidence indicates that bacterial redox proteins such as cupredoxins
andcytochromes, that are normally involved in electron transfer during respiration, can …

Activation of extracellular signal-regulated kinase mediates apoptosis induced by uropathogenic Escherichia coli toxins via nitric oxide synthase: protective role of …

M Chen, W Bao, R Aizman, P Huang… - The Journal of …, 2004 - academic.oup.com
Pyelonephritis is a risk factor for renal tubular epithelial cell damage in children. The inter-
and intracellular regulator nitric oxide (NO) plays a role in the modulation of cellular viability …

Rusticyanin, a bacterial electron transfer protein, causes G1 arrest and apoptosis in human cancer cells

T Yamada, Y Hiraoka, TKD Gupta, AM Chakrabarty - Cell Cycle, 2004 - Taylor & Francis
During acid mine drainage, Acidithiobacillus ferrooxidans, a nonpathogenic, acidophilic,
lithotrophic bacterium, utilizes rusticyanin to transfer electrons for the oxidation of Fe 2+ …

Modulation of mammalian cell growth and death by prokaryotic and eukaryotic cytochrome c

Y Hiraoka, T Yamada, M Goto… - Proceedings of the …, 2004 - National Acad Sciences
Cytochrome c 551, an 8,685-Da haem-containing protein, is known to be involved in
electron transfer during dissimilative denitrification by Pseudomonas aeruginosa. Both …

Microbial based therapy of cancer: a new twist to an age old practice

V Punj, D Saint-Dic, S Daghfal… - Cancer Biology & …, 2004 - Taylor & Francis
The use of bacteria in the regression of tumors has long been known. Various approaches
for using bacteria in cancer therapy include the use of bacteria as sensitizing agents for …

细菌氧化还原蛋白azurin 诱导U2OS 细胞凋亡过程中caspase-3 的活化

苗旭东, 杨迪生, 叶招明, 徐荣臻, 张桂娣 - 中国病理生理杂志, 2004 - cqvip.com
目的: 探讨细菌氧化还原蛋白azurin 诱导人骨肉瘤细胞U2OS 凋亡过程中是否有caspase-3
的活化. 方法: Annexin-V/PI FCM 检测细胞凋亡情况, 用Western blot 分析caspase-3 …

ATP-utilizing enzymes, purinergic receptor modulation, cupredoxins and mammalian cell death

T Yamada, AM Chakrabarty - Virulence and Gene Regulation, 2004 - Springer
Pseudomonas aeruginosa, like many other living aerobic organisms, uses oxidative
metabolism for the generation of energy in the form of ATP. ATP (phosphoanhydride bond of …